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Review

Citrus aurantium L. Active Constituents, Biological Effects and Extraction Methods. An Updated Review

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Department of Biology, Faculty of Arts and Sciences, University of Balamand, P.O. Box 100, Tripoli 1300, Lebanon
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Ecole Supérieure d’Ingénieurs de Beyrouth (ESIB), Saint-Joseph University, CST Mkalles Mar Roukos, P.O. Box 11-514, Riad El Solh, Beirut 1107 2050, Lebanon
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Centre d’Analyses et de Recherche, Unité de Recherche Technologies et Valorisation Agro-alimentaire, Faculté des Sciences, Saint-Joseph University, P.O. Box 17-5208, Riad El Solh, Beirut 1104 2020, Lebanon
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GREEN Extraction Team, INRA, UMR408, Avignon University, F-84000 Avignon, France
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Nutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avenida Vicent Andrés Estellés, s/n, 46100 Burjassot, València, Spain
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Author to whom correspondence should be addressed.
Academic Editor: Claudio Ferrante
Received: 26 August 2021 / Revised: 17 September 2021 / Accepted: 18 September 2021 / Published: 26 September 2021
(This article belongs to the Collection Feature Papers from High Cited Researchers)
Citrus genus is a prominent staple crop globally. Long-term breeding and much hybridization engendered a myriad of species, each characterized by a specific metabolism generating different secondary metabolites. Citrus aurantium L., commonly recognized as sour or bitter orange, can exceptionally be distinguished from other Citrus species by unique characteristics. It is a fruit with distinctive flavor, rich in nutrients and phytochemicals which possess different health benefits. This paper presents an overview of the most recent studies done on the matter. It intends to provide an in-depth understanding of the biological activities and medicinal uses of active constituents existing in C. aurantium. Every plant part is first discussed separately with regards to its content in active constituents. All extraction methods, their concepts and yields, used to recover these valuable molecules from their original plant matrix are thoroughly reported. View Full-Text
Keywords: C. aurantium; active constituents; medicinal uses; biological effects; extraction methods C. aurantium; active constituents; medicinal uses; biological effects; extraction methods
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MDPI and ACS Style

Maksoud, S.; Abdel-Massih, R.M.; Rajha, H.N.; Louka, N.; Chemat, F.; Barba, F.J.; Debs, E. Citrus aurantium L. Active Constituents, Biological Effects and Extraction Methods. An Updated Review. Molecules 2021, 26, 5832. https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26195832

AMA Style

Maksoud S, Abdel-Massih RM, Rajha HN, Louka N, Chemat F, Barba FJ, Debs E. Citrus aurantium L. Active Constituents, Biological Effects and Extraction Methods. An Updated Review. Molecules. 2021; 26(19):5832. https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26195832

Chicago/Turabian Style

Maksoud, Sawssan, Roula M. Abdel-Massih, Hiba N. Rajha, Nicolas Louka, Farid Chemat, Francisco J. Barba, and Espérance Debs. 2021. "Citrus aurantium L. Active Constituents, Biological Effects and Extraction Methods. An Updated Review" Molecules 26, no. 19: 5832. https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26195832

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