Next Article in Journal
Overexpression of Ferredoxin, PETF, Enhances Tolerance to Heat Stress in Chlamydomonas reinhardtii
Next Article in Special Issue
Different Effects of Androgen on the Expression of Fut1, Fut2, Fut4 and Fut9 in Male Mouse Reproductive Tract
Previous Article in Journal
Serial Changes of Serum Growth Factor Levels and Liver Regeneration after Partial Hepatectomy in Healthy Humans
Previous Article in Special Issue
The Key Enzyme of the Sialic Acid Metabolism Is Involved in Embryoid Body Formation and Expression of Marker Genes of Germ Layer Formation
Open AccessReview

Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing

College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2013, 14(10), 20890-20912; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms141020890
Received: 29 August 2013 / Revised: 20 September 2013 / Accepted: 8 October 2013 / Published: 17 October 2013
(This article belongs to the Special Issue Glycosylation and Glycoproteins)
Glycoproteins influence a broad spectrum of biological processes including cell-cell interaction, host-pathogen interaction, or protection of proteins against proteolytic degradation. The analysis of their glyco-structures and concentration levels are increasingly important in diagnosis and proteomics. Boronic acids can covalently react with cis-diols in the oligosaccharide chains of glycoproteins to form five- or six-membered cyclic esters. Based on this interaction, boronic acid-based ligands and materials have attracted much attention in both chemistry and biology as the recognition motif for enrichment and chemo/biosensing of glycoproteins in recent years. In this work, we reviewed the progress in the separation, immobilization and detection of glycoproteins with boronic acid-functionalized materials and addressed its application in sensing. View Full-Text
Keywords: glycoproteins; boronic acid; separation; sensing glycoproteins; boronic acid; separation; sensing
MDPI and ACS Style

Wang, X.; Xia, N.; Liu, L. Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing. Int. J. Mol. Sci. 2013, 14, 20890-20912. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms141020890

AMA Style

Wang X, Xia N, Liu L. Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing. International Journal of Molecular Sciences. 2013; 14(10):20890-20912. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms141020890

Chicago/Turabian Style

Wang, Xiaojin; Xia, Ning; Liu, Lin. 2013. "Boronic Acid-Based Approach for Separation and Immobilization of Glycoproteins and Its Application in Sensing" Int. J. Mol. Sci. 14, no. 10: 20890-20912. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms141020890

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop