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Review

Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis

Institute of Nanoengineering and Microsystem, National Tsing Hua University, Hsinchu 300, Taiwan
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Academic Editor: Fan-Gang Tseng
Int. J. Mol. Sci. 2015, 16(8), 16763-16777; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms160816763
Received: 1 June 2015 / Revised: 7 July 2015 / Accepted: 17 July 2015 / Published: 23 July 2015
(This article belongs to the Special Issue Single Cell Analysis in Biotechnology and Systems Biology)
This review describes the microfluidic techniques developed for the analysis of a single cell. The characteristics of microfluidic (e.g., little sample amount required, high-throughput performance) make this tool suitable to answer and to solve biological questions of interest about a single cell. This review aims to introduce microfluidic related techniques for the isolation, trapping and manipulation of a single cell. The major approaches for detection in single-cell analysis are introduced; the applications of single-cell analysis are then summarized. The review concludes with discussions of the future directions and opportunities of microfluidic systems applied in analysis of a single cell. View Full-Text
Keywords: microfluidic techniques; single-cell manipulation; single-cell analysis microfluidic techniques; single-cell manipulation; single-cell analysis
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MDPI and ACS Style

Lo, S.-J.; Yao, D.-J. Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis. Int. J. Mol. Sci. 2015, 16, 16763-16777. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms160816763

AMA Style

Lo S-J, Yao D-J. Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis. International Journal of Molecular Sciences. 2015; 16(8):16763-16777. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms160816763

Chicago/Turabian Style

Lo, Shih-Jie, and Da-Jeng Yao. 2015. "Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis" International Journal of Molecular Sciences 16, no. 8: 16763-16777. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms160816763

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