Next Article in Journal
Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex
Next Article in Special Issue
Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells
Previous Article in Journal
Advances in Lipidomics for Cancer Biomarkers Discovery
Previous Article in Special Issue
Microarray Expression Profiling of Long Non-Coding RNAs Involved in Nasopharyngeal Carcinoma Metastasis

Roles of MicroRNA across Prenatal and Postnatal Periods

Biochemistry, Microbiology & Immunology Department, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H8M5, Canada
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Current address: Labo’Life France, Pescalis, Les Magnys, 79320 Moutiers-sous-Chantemerle, France.
Academic Editor: Martin Pichler
Int. J. Mol. Sci. 2016, 17(12), 1994;
Received: 16 October 2016 / Revised: 11 November 2016 / Accepted: 17 November 2016 / Published: 28 November 2016
(This article belongs to the Collection Regulation by Non-Coding RNAs)
Communication between mother and offspring in mammals starts at implantation via the maternal–placental–fetal axis, and continues postpartum via milk targeted to the intestinal mucosa. MicroRNAs (miRNAs), short, noncoding single-stranded RNAs, of about 22 nucleotides in length, are actively involved in many developmental and physiological processes. Here we highlight the role of miRNA in the dynamic signaling that guides infant development, starting from implantation of conceptus and persisting through the prenatal and postnatal periods. miRNAs in body fluids, particularly in amniotic fluid, umbilical cord blood, and breast milk may offer new opportunities to investigate physiological and/or pathological molecular mechanisms that portend to open novel research avenues for the identification of noninvasive biomarkers. View Full-Text
Keywords: maternal-offspring crosstalk; microRNA; noninvasive biomarkers; breast milk maternal-offspring crosstalk; microRNA; noninvasive biomarkers; breast milk
Show Figures

Graphical abstract

MDPI and ACS Style

Floris, I.; Kraft, J.D.; Altosaar, I. Roles of MicroRNA across Prenatal and Postnatal Periods. Int. J. Mol. Sci. 2016, 17, 1994.

AMA Style

Floris I, Kraft JD, Altosaar I. Roles of MicroRNA across Prenatal and Postnatal Periods. International Journal of Molecular Sciences. 2016; 17(12):1994.

Chicago/Turabian Style

Floris, Ilaria, Jamie D. Kraft, and Illimar Altosaar. 2016. "Roles of MicroRNA across Prenatal and Postnatal Periods" International Journal of Molecular Sciences 17, no. 12: 1994.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop