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Roles of MicroRNA across Prenatal and Postnatal Periods

Biochemistry, Microbiology & Immunology Department, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H8M5, Canada
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Current address: Labo’Life France, Pescalis, Les Magnys, 79320 Moutiers-sous-Chantemerle, France.
Academic Editor: Martin Pichler
Int. J. Mol. Sci. 2016, 17(12), 1994; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17121994
Received: 16 October 2016 / Revised: 11 November 2016 / Accepted: 17 November 2016 / Published: 28 November 2016
(This article belongs to the Collection Regulation by Non-Coding RNAs)
Communication between mother and offspring in mammals starts at implantation via the maternal–placental–fetal axis, and continues postpartum via milk targeted to the intestinal mucosa. MicroRNAs (miRNAs), short, noncoding single-stranded RNAs, of about 22 nucleotides in length, are actively involved in many developmental and physiological processes. Here we highlight the role of miRNA in the dynamic signaling that guides infant development, starting from implantation of conceptus and persisting through the prenatal and postnatal periods. miRNAs in body fluids, particularly in amniotic fluid, umbilical cord blood, and breast milk may offer new opportunities to investigate physiological and/or pathological molecular mechanisms that portend to open novel research avenues for the identification of noninvasive biomarkers. View Full-Text
Keywords: maternal-offspring crosstalk; microRNA; noninvasive biomarkers; breast milk maternal-offspring crosstalk; microRNA; noninvasive biomarkers; breast milk
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MDPI and ACS Style

Floris, I.; Kraft, J.D.; Altosaar, I. Roles of MicroRNA across Prenatal and Postnatal Periods. Int. J. Mol. Sci. 2016, 17, 1994. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17121994

AMA Style

Floris I, Kraft JD, Altosaar I. Roles of MicroRNA across Prenatal and Postnatal Periods. International Journal of Molecular Sciences. 2016; 17(12):1994. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17121994

Chicago/Turabian Style

Floris, Ilaria, Jamie D. Kraft, and Illimar Altosaar. 2016. "Roles of MicroRNA across Prenatal and Postnatal Periods" International Journal of Molecular Sciences 17, no. 12: 1994. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17121994

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