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Saponin-Based Nanoemulsification Improves the Antioxidant Properties of Vitamin A and E in AML-12 Cells

Department of Food and Biotechnology, Korea University, 2511 Sejongro, Jochiwon, Sejong 339-700, Korea
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Academic Editor: Maurizio Battino
Int. J. Mol. Sci. 2016, 17(9), 1406; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17091406
Received: 27 June 2016 / Revised: 27 June 2016 / Accepted: 22 August 2016 / Published: 26 August 2016
(This article belongs to the Section Bioactives and Nutraceuticals)
Our work aimed to investigate the protective effects of saponin-based nanoemulsions of vitamin A and E against oxidative stress-induced cellular damage in AML-12 cells. Saponin nanoemulsions of vitamin A (SAN) and vitamin E (SEN) were prepared by high-pressure homogenization and characterized in terms of size, zeta potential, and polydispersity index. SEN and SAN protect AML-12 cells against oxidative stress-induced cellular damage more efficiently via scavenging reactive oxygen species (ROS), and reducing DNA damage, protein carbonylation, and lipid peroxidation. These results provide valuable information for the development of nanoemulsion-based delivery systems that would improve the antioxidant properties of vitamin A and E. View Full-Text
Keywords: vitamin A; vitamin E; nanoemulsification; saponin; antioxidant capacity vitamin A; vitamin E; nanoemulsification; saponin; antioxidant capacity
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MDPI and ACS Style

Choudhry, Q.N.; Kim, M.J.; Kim, T.G.; Pan, J.H.; Kim, J.H.; Park, S.J.; Lee, J.H.; Kim, Y.J. Saponin-Based Nanoemulsification Improves the Antioxidant Properties of Vitamin A and E in AML-12 Cells. Int. J. Mol. Sci. 2016, 17, 1406. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17091406

AMA Style

Choudhry QN, Kim MJ, Kim TG, Pan JH, Kim JH, Park SJ, Lee JH, Kim YJ. Saponin-Based Nanoemulsification Improves the Antioxidant Properties of Vitamin A and E in AML-12 Cells. International Journal of Molecular Sciences. 2016; 17(9):1406. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17091406

Chicago/Turabian Style

Choudhry, Qaisra N., Mi J. Kim, Tae G. Kim, Jeong H. Pan, Jun H. Kim, Sung J. Park, Jin H. Lee, and Young J. Kim 2016. "Saponin-Based Nanoemulsification Improves the Antioxidant Properties of Vitamin A and E in AML-12 Cells" International Journal of Molecular Sciences 17, no. 9: 1406. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms17091406

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