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Review

Soy Lecithin-Derived Liposomal Delivery Systems: Surface Modification and Current Applications

1
Institute of Research and Development, Duy Tan University, Danang 550000, Vietnam
2
Faculty of Pharmacy, Lac Hong University, Buu Long Ward, Bien Hoa City, Dong Nai Province 810000, Vietnam
3
Biomaterials and Nanotechnology Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City 700000, Vietnam
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(19), 4706; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20194706
Received: 27 August 2019 / Revised: 15 September 2019 / Accepted: 20 September 2019 / Published: 23 September 2019
The development of natural phospholipids for nanostructured drug delivery systems has attracted much attention in the past decades. Lecithin that was derived from naturally occurring in soybeans (SL) has introduced some auspicious accomplishments to the drug carrying aspect, like effectual encapsulation, controlled release, and successful delivery of the curative factors to intracellular regions in which they procure these properties from their flexible physicochemical and biophysical properties, such as large aqueous center and biocompatible lipid, self-assembly, tunable properties, and high loading capacity. Despite the almost perfect properties as a drug carrier, liposome is known to be quite quickly eliminated from the body systems. The surface modification of liposomes has been investigated in many studies to overcome this drawback. In this review, we intensively discussed the surface-modified liposomes that enhancing the targeting, cellular uptake, and therapeutic response. Moreover, the recent applications of soy lecithin-derived liposome, focusing on cancer treatment, brain targeting, and vaccinology, are also summarized. View Full-Text
Keywords: soy lecithin; liposome; drug delivery system; surface modification soy lecithin; liposome; drug delivery system; surface modification
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MDPI and ACS Style

Le, N.T.T.; Cao, V.D.; Nguyen, T.N.Q.; Le, T.T.H.; Tran, T.T.; Hoang Thi, T.T. Soy Lecithin-Derived Liposomal Delivery Systems: Surface Modification and Current Applications. Int. J. Mol. Sci. 2019, 20, 4706. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20194706

AMA Style

Le NTT, Cao VD, Nguyen TNQ, Le TTH, Tran TT, Hoang Thi TT. Soy Lecithin-Derived Liposomal Delivery Systems: Surface Modification and Current Applications. International Journal of Molecular Sciences. 2019; 20(19):4706. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20194706

Chicago/Turabian Style

Le, Ngoc T.T., Van D. Cao, Thi N.Q. Nguyen, Thi T.H. Le, Thach T. Tran, and Thai T. Hoang Thi 2019. "Soy Lecithin-Derived Liposomal Delivery Systems: Surface Modification and Current Applications" International Journal of Molecular Sciences 20, no. 19: 4706. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms20194706

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