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Innovative Biomaterials for Bone Regrowth

Department of Morphology, Surgery, and Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy
Department of Surgery, University of Verona, 37129 Verona, Italy
Research Centre for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, 44121 Ferrara, Italy
IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy
Authors to whom correspondence should be addressed.
These authors contributed equally to the work.
Int. J. Mol. Sci. 2019, 20(3), 618;
Received: 9 January 2019 / Revised: 25 January 2019 / Accepted: 29 January 2019 / Published: 31 January 2019
(This article belongs to the Special Issue Cell-Biomaterial Interaction 2019)
The regenerative medicine, a new discipline that merges biological sciences and the fundamental of engineering to develop biological substitutes, has greatly benefited from recent advances in the material engineering and the role of stem cells in tissue regeneration. Regenerative medicine strategies, involving the combination of biomaterials/scaffolds, cells, and bioactive agents, have been of great interest especially for the repair of damaged bone and bone regrowth. In the last few years, the life expectancy of our population has progressively increased. Aging has highlighted the need for intervention on human bone with biocompatible materials that show high performance for the regeneration of the bone, efficiently and in a short time. In this review, the different aspects of tissue engineering applied to bone engineering were taken into consideration. The first part of this review introduces the bone cellular biology/molecular genetics. Data on biomaterials, stem cells, and specific growth factors for the bone regrowth are reported in this review. View Full-Text
Keywords: regenerative medicine; bone; biomaterial; stem cells; growth factors regenerative medicine; bone; biomaterial; stem cells; growth factors
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MDPI and ACS Style

Iaquinta, M.R.; Mazzoni, E.; Manfrini, M.; D’Agostino, A.; Trevisiol, L.; Nocini, R.; Trombelli, L.; Barbanti-Brodano, G.; Martini, F.; Tognon, M. Innovative Biomaterials for Bone Regrowth. Int. J. Mol. Sci. 2019, 20, 618.

AMA Style

Iaquinta MR, Mazzoni E, Manfrini M, D’Agostino A, Trevisiol L, Nocini R, Trombelli L, Barbanti-Brodano G, Martini F, Tognon M. Innovative Biomaterials for Bone Regrowth. International Journal of Molecular Sciences. 2019; 20(3):618.

Chicago/Turabian Style

Iaquinta, Maria R., Elisa Mazzoni, Marco Manfrini, Antonio D’Agostino, Lorenzo Trevisiol, Riccardo Nocini, Leonardo Trombelli, Giovanni Barbanti-Brodano, Fernanda Martini, and Mauro Tognon. 2019. "Innovative Biomaterials for Bone Regrowth" International Journal of Molecular Sciences 20, no. 3: 618.

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