Next Article in Journal
Synthesis, Properties, and Biological Applications of Metallic Alloy Nanoparticles
Next Article in Special Issue
Age-Associated Salivary MicroRNA Biomarkers for Oculopharyngeal Muscular Dystrophy
Previous Article in Journal
Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes
Previous Article in Special Issue
Evaluation of Salivary Cytokines and Vitamin D Levels in Periodontopathic Patients
Review

Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies

1
Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences (Ceuta), University of Granada, 51001 Granada, Spain
2
Instituto Investigación Biosanitaria, ibs.Granada, 18012 Granada, Spain
3
Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain
4
Biomedical Group (BIO277), Department of Stomatology, School of Dentistry, University of Granada, 18071 Granada, Spain
5
Institute of Neuroscience, University of Granada, 18016 Granada, Spain
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(14), 5173; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21145173
Received: 17 June 2020 / Revised: 10 July 2020 / Accepted: 15 July 2020 / Published: 21 July 2020
Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner—and the results of its analysis complement clinical and histopathological findings in the diagnosis of multiple diseases. The objective of this review was to offer an update on the contribution of salivary biomarkers to the diagnosis and prognosis of diseases of the oral cavity, including oral lichen planus, periodontitis, Sjögren’s syndrome, oral leukoplakia, peri-implantitis, and medication-related osteonecrosis of the jaw. Salivary biomarkers such as interleukins, growth factors, enzymes, and other biomolecules have proven useful in the diagnosis and follow-up of these diseases, facilitating the early evaluation of malignization risk and the monitoring of disease progression and response to treatment. However, further studies are required to identify new biomarkers and verify their reported role in the diagnosis and/or prognosis of oral diseases. View Full-Text
Keywords: salivary biomarker; cytokines; oral pathology; diagnosis salivary biomarker; cytokines; oral pathology; diagnosis
Show Figures

Graphical abstract

MDPI and ACS Style

Melguizo-Rodríguez, L.; Costela-Ruiz, V.J.; Manzano-Moreno, F.J.; Ruiz, C.; Illescas-Montes, R. Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies. Int. J. Mol. Sci. 2020, 21, 5173. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21145173

AMA Style

Melguizo-Rodríguez L, Costela-Ruiz VJ, Manzano-Moreno FJ, Ruiz C, Illescas-Montes R. Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies. International Journal of Molecular Sciences. 2020; 21(14):5173. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21145173

Chicago/Turabian Style

Melguizo-Rodríguez, Lucía, Victor J. Costela-Ruiz, Francisco J. Manzano-Moreno, Concepción Ruiz, and Rebeca Illescas-Montes. 2020. "Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies" International Journal of Molecular Sciences 21, no. 14: 5173. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21145173

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop