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Review

Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy

by 1,†, 1,†, 2, 1 and 1,*
1
Institute of Biomedical Materials and Engineering, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, China
2
Qingdao Institute of Measurement Technology, Qingdao 266000, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to the paper.
Int. J. Mol. Sci. 2020, 21(23), 9159; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21239159
Received: 19 November 2020 / Revised: 29 November 2020 / Accepted: 30 November 2020 / Published: 1 December 2020
Chemotherapy is still the most direct and effective means of cancer therapy nowadays. The proposal of drug delivery systems (DDSs) has effectively improved many shortcomings of traditional chemotherapy drugs. The technical support of DDSs lies in their excellent material properties. Polysaccharides include a series of natural polymers, such as chitosan, hyaluronic acid, and alginic acid. These polysaccharides have good biocompatibility and degradability, and they are easily chemical modified. Therefore, polysaccharides are ideal candidate materials to construct DDSs, and their clinical application prospects have been favored by researchers. On the basis of versatile types of polysaccharides, this review elaborates their applications from strategic design to cancer therapy. The construction and modification methods of polysaccharide-based DDSs are specifically explained, and the latest research progress of polysaccharide-based DDSs in cancer therapy are also summarized. The purpose of this review is to provide a reference for the design and preparation of polysaccharide-based DDSs with excellent performance. View Full-Text
Keywords: polysaccharide; drug delivery system (DDS); chemotherapy; cancer therapy polysaccharide; drug delivery system (DDS); chemotherapy; cancer therapy
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MDPI and ACS Style

Sun, Y.; Jing, X.; Ma, X.; Feng, Y.; Hu, H. Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy. Int. J. Mol. Sci. 2020, 21, 9159. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21239159

AMA Style

Sun Y, Jing X, Ma X, Feng Y, Hu H. Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy. International Journal of Molecular Sciences. 2020; 21(23):9159. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21239159

Chicago/Turabian Style

Sun, Yanzhen, Xiaodong Jing, Xiaoli Ma, Yinglong Feng, and Hao Hu. 2020. "Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy" International Journal of Molecular Sciences 21, no. 23: 9159. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms21239159

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