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Article

Pyridazino-1,3a,6a-Triazapentalenes as Versatile Fluorescent Probes: Impact of Their Post-Functionalization and Application for Cellular Imaging

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Institut de Chimie Organique et Analytique—ICOA UMR7311, Rue de Chartres, CEDEX 2, 45100 Orléans, France
2
Centre de Biophysique Moléculaire CNRS UPR 4301, Rue Charles Sadron, CEDEX 2, 45071 Orléans, France
*
Authors to whom correspondence should be addressed.
Academic Editor: Kiryl D. Piatkevich
Int. J. Mol. Sci. 2021, 22(12), 6645; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22126645
Received: 18 May 2021 / Revised: 18 June 2021 / Accepted: 18 June 2021 / Published: 21 June 2021
Pyridazino-1,3a,6a-triazapentalenes (PyTAP) are compact fused 6/5/5 tricyclic scaffolds which exhibit promising fluorescent properties. Chemically stable, they can be post-functionalized using standard Pd-catalyzed cross-coupling chemistry. Several original PyTAP bearing additional unsaturated substituents in positions 2 and 8 were synthetized and their spectroscopic properties analyzed. They have been successfully tested as fluorescent probes for cellular imaging. View Full-Text
Keywords: pyridazino-1,3a,6a-triazapentalenes; fluorophores; photostability; cell imaging; fluorescence pyridazino-1,3a,6a-triazapentalenes; fluorophores; photostability; cell imaging; fluorescence
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MDPI and ACS Style

Sirbu, D.; Chopin, N.; Martinić, I.; Ndiaye, M.; Eliseeva, S.V.; Hiebel, M.-A.; Petoud, S.; Suzenet, F. Pyridazino-1,3a,6a-Triazapentalenes as Versatile Fluorescent Probes: Impact of Their Post-Functionalization and Application for Cellular Imaging. Int. J. Mol. Sci. 2021, 22, 6645. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22126645

AMA Style

Sirbu D, Chopin N, Martinić I, Ndiaye M, Eliseeva SV, Hiebel M-A, Petoud S, Suzenet F. Pyridazino-1,3a,6a-Triazapentalenes as Versatile Fluorescent Probes: Impact of Their Post-Functionalization and Application for Cellular Imaging. International Journal of Molecular Sciences. 2021; 22(12):6645. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22126645

Chicago/Turabian Style

Sirbu, Doina, Nicolas Chopin, Ivana Martinić, Moussa Ndiaye, Svetlana V. Eliseeva, Marie-Aude Hiebel, Stéphane Petoud, and Franck Suzenet. 2021. "Pyridazino-1,3a,6a-Triazapentalenes as Versatile Fluorescent Probes: Impact of Their Post-Functionalization and Application for Cellular Imaging" International Journal of Molecular Sciences 22, no. 12: 6645. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22126645

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