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Stem Cells in Autologous Microfragmented Adipose Tissue: Current Perspectives in Osteoarthritis Disease

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Department of Plastic and Reconstructive Surgery-Hand Surgery Unit, Azienda ‘Ospedali Riuniti’, 60126 Ancona, Italy
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Clinical Orthopaedics, Department of Clinical and Molecular Science, Polytechnic University of Marche, 60126 Ancona, Italy
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Department of Neuroscience, Biomedicine and Movement, Human Anatomy and Histology Section, University of Verona, 37135 Verona, Italy
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Fidia Advanced Biopolymers, 35031 Abano Terme, Italy
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Clinic of Plastic and Reconstructive Surgery, Academic Hospital of Udine, Department of Medical Area (DAME), University of Udine, 33100 Udine, Italy
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Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy
*
Authors to whom correspondence should be addressed.
Academic Editor: Silvia Panseri
Int. J. Mol. Sci. 2021, 22(19), 10197; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms221910197
Received: 22 August 2021 / Revised: 9 September 2021 / Accepted: 14 September 2021 / Published: 22 September 2021
Osteoarthritis (OA) is a chronic debilitating disorder causing pain and gradual degeneration of weight-bearing joints with detrimental effects on cartilage volume as well as cartilage damage, generating inflammation in the joint structure. The etiology of OA is multifactorial. Currently, therapies are mainly addressing the physical and occupational aspects of osteoarthritis using pharmacologic pain treatment and/or surgery to manage the symptomatology of the disease with no specific regard to disease progression or prevention. Herein, we highlight alternative therapeutics for OA specifically considering innovative and encouraging translational methods with the use of adipose mesenchymal stem cells. View Full-Text
Keywords: osteoarthritis; stromal vascular fraction; mechanical disaggregation; regenerative surgery; adipo micrografts osteoarthritis; stromal vascular fraction; mechanical disaggregation; regenerative surgery; adipo micrografts
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MDPI and ACS Style

De Francesco, F.; Gravina, P.; Busato, A.; Farinelli, L.; Soranzo, C.; Vidal, L.; Zingaretti, N.; Zavan, B.; Sbarbati, A.; Riccio, M.; Gigante, A. Stem Cells in Autologous Microfragmented Adipose Tissue: Current Perspectives in Osteoarthritis Disease. Int. J. Mol. Sci. 2021, 22, 10197. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms221910197

AMA Style

De Francesco F, Gravina P, Busato A, Farinelli L, Soranzo C, Vidal L, Zingaretti N, Zavan B, Sbarbati A, Riccio M, Gigante A. Stem Cells in Autologous Microfragmented Adipose Tissue: Current Perspectives in Osteoarthritis Disease. International Journal of Molecular Sciences. 2021; 22(19):10197. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms221910197

Chicago/Turabian Style

De Francesco, Francesco, Pasquale Gravina, Alice Busato, Luca Farinelli, Carlo Soranzo, Luis Vidal, Nicola Zingaretti, Barbara Zavan, Andrea Sbarbati, Michele Riccio, and Antonio Gigante. 2021. "Stem Cells in Autologous Microfragmented Adipose Tissue: Current Perspectives in Osteoarthritis Disease" International Journal of Molecular Sciences 22, no. 19: 10197. https://0-doi-org.brum.beds.ac.uk/10.3390/ijms221910197

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