|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mean Table of SI (Without Exclusion) µg/l |
|
|
|
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
Mean |
|
Placebo |
0 |
49 |
47 |
41 |
98 |
13 |
49 |
21 |
85 |
16 |
28 |
44 |
44,6 |
|
|
60 |
16 |
68 |
54 |
43 |
16 |
52 |
16 |
34 |
22 |
26 |
43 |
35,5 |
|
|
120 |
19 |
27 |
64 |
41 |
23 |
39 |
13 |
31 |
23 |
25 |
26 |
30,1 |
|
|
180 |
15 |
35 |
51 |
30 |
16 |
44 |
12 |
36 |
18 |
25 |
31 |
28,5 |
|
|
240 |
22 |
24 |
68 |
34 |
16 |
40 |
19 |
33 |
10 |
26 |
33 |
29,5 |
|
µ |
|
|
300 |
15 |
28 |
63 |
35 |
17 |
33 |
20 |
32 |
13 |
33 |
32 |
29,2 |
|
FeSO4 6,5 |
0 |
79 |
16 |
30 |
42 |
9 |
51 |
16 |
74 |
12 |
23 |
34 |
35,1 |
|
|
60 |
68 |
18 |
51 |
32 |
14 |
46 |
12 |
69 |
12 |
20 |
23 |
33,2 |
|
|
120 |
54 |
24 |
48 |
29 |
14 |
44 |
12 |
63 |
21 |
14 |
29 |
32,0 |
|
|
180 |
41 |
15 |
44 |
26 |
6 |
34 |
14 |
17 |
52 |
10 |
24 |
25,7 |
|
|
240 |
31 |
12 |
51 |
27 |
15 |
27 |
10 |
39 |
17 |
9 |
24 |
23,8 |
|
|
300 |
25 |
23 |
47 |
22 |
14 |
25 |
17 |
32 |
21 |
16 |
16 |
23,5 |
|
FeSO4 65 |
0 |
23 |
38 |
26 |
47 |
14 |
26 |
13 |
24 |
18 |
23 |
18 |
24,5 |
|
|
60 |
30 |
146 |
55 |
44 |
44 |
82 |
32 |
54 |
34 |
140 |
27 |
62,5 |
|
|
120 |
90 |
113 |
111 |
108 |
34 |
74 |
21 |
42 |
26 |
155 |
33 |
73,4 |
|
|
180 |
110 |
108 |
101 |
111 |
33 |
68 |
23 |
43 |
26 |
119 |
59 |
72,8 |
|
|
240 |
88 |
86 |
69 |
83 |
28 |
66 |
20 |
36 |
21 |
90 |
118 |
64,1 |
|
|
300 |
78 |
76 |
55 |
89 |
16 |
66 |
27 |
24 |
18 |
70 |
127 |
58,7 |
|
NaFeEDTA 6,5 |
0 |
18 |
23 |
13 |
22 |
19 |
19 |
23 |
44 |
18 |
41 |
23 |
23,9 |
|
|
60 |
14 |
31 |
29 |
24 |
36 |
22 |
55 |
43 |
24 |
31 |
29 |
30,7 |
|
|
120 |
21 |
41 |
23 |
40 |
41 |
22 |
34 |
53 |
26 |
36 |
51 |
35,3 |
|
|
180 |
18 |
39 |
26 |
36 |
38 |
20 |
28 |
58 |
27 |
29 |
44 |
33,0 |
|
|
240 |
11 |
33 |
26 |
40 |
34 |
13 |
23 |
45 |
19 |
33 |
41 |
28,9 |
|
|
300 |
15 |
24 |
26 |
37 |
26 |
13 |
25 |
42 |
15 |
45 |
42 |
28,2 |
|
NaFeEDTA 65 |
0 |
6 |
16 |
35 |
36 |
15 |
14 |
18 |
42 |
15 |
37 |
23 |
23,4 |
|
|
60 |
14 |
27 |
92 |
47 |
123 |
19 |
26 |
55 |
10 |
122 |
124 |
59,9 |
|
|
120 |
39 |
107 |
130 |
85 |
151 |
8 |
57 |
91 |
17 |
110 |
188 |
89,4 |
|
|
180 |
78 |
156 |
161 |
85 |
143 |
16 |
48 |
100 |
17 |
102 |
170 |
97,8 |
|
|
240 |
104 |
179 |
145 |
83 |
97 |
16 |
45 |
108 |
27 |
83 |
132 |
92,6 |
|
|
300 |
109 |
185 |
132 |
62 |
82 |
7 |
37 |
99 |
23 |
65 |
139 |
85,5 |
|
|
Note: |
|
Hemolytic Condition |
|
|
|
|
|
|
|
|
|
|
|
Modification Result
of SI (With Exclusion); µg/l |
|
|
Time |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
Mean |
Subject |
|
Placebo |
0 |
Hemolysis |
47 |
41 |
Hemolysis |
13 |
49 |
21 |
Hemolysis |
16 |
28 |
Hemolysis |
30,7 |
7 |
|
|
60 |
16 |
Hemolysis |
54 |
43 |
16 |
52 |
16 |
34 |
22 |
26 |
43 |
32,2 |
10 |
|
|
120 |
19 |
27 |
64 |
41 |
23 |
39 |
13 |
31 |
23 |
25 |
26 |
30,1 |
11 |
|
|
180 |
15 |
35 |
51 |
30 |
16 |
44 |
12 |
36 |
18 |
25 |
31 |
28,5 |
11 |
|
|
240 |
22 |
24 |
68 |
34 |
16 |
40 |
19 |
33 |
10 |
26 |
33 |
29,5 |
11 |
|
|
300 |
15 |
28 |
63 |
35 |
17 |
33 |
20 |
32 |
13 |
33 |
32 |
29,2 |
11 |
|
FeSO4 6,5 |
0 |
Hemolysis |
16 |
30 |
|
9 |
|
16 |
74 |
|
23 |
23 |
27,3 |
7 |
|
|
60 |
68 |
18 |
51 |
|
14 |
|
12 |
69 |
|
20 |
23 |
34,4 |
8 |
|
|
120 |
54 |
24 |
48 |
Skip cause |
14 |
|
12 |
63 |
Skip cause |
14 |
29 |
32,3 |
8 |
|
|
180 |
41 |
15 |
44 |
CRP 15.1 |
6 |
|
14 |
17 |
CRP 28.5 |
10 |
24 |
21,4 |
8 |
|
|
240 |
31 |
12 |
51 |
|
15 |
|
10 |
39 |
Fer>26.8 |
9 |
24 |
23,9 |
8 |
|
|
300 |
25 |
23 |
47 |
|
14 |
|
17 |
32 |
|
16 |
16 |
23,8 |
8 |
|
FeSO4 65 |
0 |
23 |
38 |
26 |
47 |
14 |
|
13 |
24 |
|
23 |
18 |
25,1 |
9 |
|
|
60 |
30 |
Hemoysis |
55 |
44 |
44 |
|
32 |
54 |
|
140 |
27 |
53,3 |
8 |
|
|
120 |
90 |
113 |
111 |
108 |
34 |
|
21 |
42 |
|
155 |
33 |
78,6 |
9 |
|
|
180 |
110 |
108 |
101 |
111 |
33 |
|
23 |
43 |
|
119 |
59 |
78,6 |
9 |
|
|
240 |
88 |
86 |
69 |
83 |
28 |
|
20 |
36 |
|
90 |
118 |
68,7 |
9 |
|
|
300 |
78 |
76 |
55 |
89 |
16 |
|
27 |
24 |
|
70 |
127 |
62,4 |
9 |
|
NaFeEDTA 6,5 |
0 |
18 |
23 |
13 |
|
19 |
|
23 |
44 |
|
41 |
23 |
25,5 |
8 |
|
|
60 |
14 |
31 |
29 |
|
36 |
|
55 |
43 |
|
31 |
29 |
33,5 |
8 |
|
|
120 |
21 |
41 |
23 |
|
41 |
Skip cause |
34 |
53 |
|
36 |
51 |
37,5 |
8 |
|
|
180 |
18 |
39 |
26 |
|
38 |
CRP 13.3 |
28 |
58 |
|
29 |
44 |
35,0 |
8 |
|
|
240 |
11 |
33 |
26 |
|
34 |
|
23 |
45 |
|
33 |
41 |
30,8 |
8 |
|
|
300 |
15 |
24 |
26 |
|
26 |
|
25 |
42 |
|
45 |
42 |
30,6 |
8 |
|
NaFeEDTA 65 |
0 |
6 |
16 |
35 |
36 |
15 |
|
18 |
42 |
|
37 |
23 |
25,3 |
9 |
|
|
60 |
14 |
27 |
92 |
47 |
123 |
|
26 |
55 |
|
122 |
124 |
70,0 |
9 |
|
|
120 |
39 |
107 |
130 |
85 |
151 |
Skip cause |
57 |
91 |
Skip cause |
110 |
188 |
106,4 |
9 |
|
|
180 |
78 |
156 |
161 |
85 |
143 |
CRP 110 |
48 |
100 |
CRP 47 |
102 |
170 |
115,9 |
9 |
|
|
240 |
104 |
179 |
145 |
83 |
97 |
Fer > 50% |
45 |
108 |
Fer > 50% |
83 |
132 |
108,4 |
9 |
|
|
300 |
109 |
185 |
132 |
62 |
82 |
|
37 |
99 |
|
65 |
139 |
101,1 |
9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Note : |
|
Hemolytic Condition |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drop Out |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Modification Result
of SI (With Exclusion); µg/l; Start from 0 |
|
|
Time |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
Mean |
Subject |
|
Placebo |
0 |
Hemolysis |
0 |
0 |
Hemolysis |
0 |
0 |
0 |
Hemolysis |
0 |
0 |
Hemolysis |
0,0 |
7 |
|
|
60 |
-7 |
Hemolysis |
13 |
21 |
3 |
3 |
-5 |
10 |
6 |
-2 |
20 |
6,2 |
10 |
|
|
120 |
-4 |
-20 |
23 |
19 |
10 |
-10 |
-8 |
7 |
7 |
-3 |
3 |
2,2 |
11 |
|
|
180 |
-8 |
-12 |
10 |
8 |
3 |
-5 |
-9 |
12 |
2 |
-3 |
8 |
0,5 |
11 |
|
|
240 |
-1 |
-23 |
27 |
12 |
3 |
-9 |
-2 |
9 |
-6 |
-2 |
10 |
1,6 |
11 |
|
|
300 |
-8 |
-19 |
22 |
13 |
4 |
-16 |
-1 |
8 |
-3 |
5 |
9 |
1,3 |
11 |
|
FeSO4 6,5 |
0 |
Hemolysis |
0 |
0 |
|
0 |
|
0 |
0 |
|
0 |
0 |
0,0 |
7 |
|
|
60 |
45 |
2 |
21 |
|
5 |
|
-4 |
-5 |
|
-3 |
0 |
7,6 |
8 |
|
|
120 |
31 |
8 |
18 |
Skip cause |
5 |
|
-4 |
-11 |
Skip cause |
-9 |
6 |
5,5 |
8 |
|
|
180 |
18 |
-1 |
14 |
CRP 15.1 |
-3 |
|
-2 |
-57 |
CRP 28.5 |
-13 |
1 |
-5,4 |
8 |
|
|
240 |
8 |
-4 |
21 |
|
6 |
|
-6 |
-35 |
Fer>26.8 |
-14 |
1 |
-2,9 |
8 |
|
|
300 |
2 |
7 |
17 |
|
5 |
|
1 |
-42 |
|
-7 |
-7 |
-3,0 |
8 |
|
FeSO4 65 |
0 |
0 |
0 |
0 |
0 |
0 |
|
0 |
0 |
|
0 |
0 |
0,0 |
9 |
|
|
60 |
7 |
Hemoysis |
29 |
-3 |
30 |
|
19 |
30 |
|
117 |
9 |
29,8 |
8 |
|
|
120 |
67 |
75 |
85 |
61 |
20 |
|
8 |
18 |
|
132 |
15 |
53,4 |
9 |
|
|
180 |
87 |
70 |
75 |
64 |
19 |
|
10 |
19 |
|
96 |
41 |
53,4 |
9 |
|
|
240 |
65 |
48 |
43 |
36 |
14 |
|
7 |
12 |
|
67 |
104 |
44,0 |
9 |
|
|
300 |
55 |
38 |
29 |
42 |
2 |
|
14 |
0 |
|
47 |
109 |
37,3 |
9 |
|
NaFeEDTA 6,5 |
0 |
0 |
0 |
0 |
|
0 |
|
0 |
0 |
|
0 |
0 |
0,0 |
8 |
|
|
60 |
-4 |
8 |
16 |
|
17 |
|
32 |
-1 |
|
-10 |
6 |
8,0 |
8 |
|
|
120 |
3 |
18 |
10 |
|
22 |
Skip cause |
11 |
9 |
|
-5 |
28 |
12,0 |
8 |
|
|
180 |
0 |
16 |
13 |
|
19 |
CRP 13.3 |
5 |
14 |
|
-12 |
21 |
9,5 |
8 |
|
|
240 |
-7 |
10 |
13 |
|
15 |
|
0 |
1 |
|
-8 |
18 |
5,3 |
8 |
|
|
300 |
-3 |
1 |
13 |
|
7 |
|
2 |
-2 |
|
4 |
19 |
5,1 |
8 |
|
NaFeEDTA 65 |
0 |
0 |
0 |
0 |
0 |
0 |
|
0 |
0 |
|
0 |
0 |
0,0 |
9 |
|
|
60 |
8 |
11 |
57 |
11 |
108 |
|
8 |
13 |
|
85 |
101 |
44,7 |
9 |
|
|
120 |
33 |
91 |
95 |
49 |
136 |
Skip cause |
39 |
49 |
Skip cause |
73 |
165 |
81,1 |
9 |
|
|
180 |
72 |
140 |
126 |
49 |
128 |
CRP 110 |
30 |
58 |
CRP 47 |
65 |
147 |
90,6 |
9 |
|
|
240 |
98 |
163 |
110 |
47 |
76 |
Fer > 50% |
27 |
66 |
Fer > 50% |
46 |
109 |
82,4 |
9 |
|
|
300 |
103 |
169 |
97 |
26 |
67 |
|
19 |
57 |
|
28 |
116 |
75,8 |
9 |
|
|
|
Note : |
|
Hemolytic Condition |
|
|
|
|
Drop Out |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|