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Review

Gold Nanoparticles: A New Golden Era in Oncology?

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UOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, Italy
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Dipartimento di Scienze della Vita e dell’Ambiente, University of Cagliari, 09042 Cagliari, Italy
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UOC Radiologia, AOU Cagliari, University of Cagliari, 09042 Cagliari, Italy
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Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA
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Department of Pathology, Genk Regional Ziekenhuis, 3600 Genk, Belgium
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UOC Oncologia Medica, AOU Cagliari, University of Cagliari, 09042 Cagliari, Italy
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Pathologische Ontleedkunde K.U. Leuven, 3000 Leuven, Belgium
*
Authors to whom correspondence should be addressed.
Pharmaceuticals 2020, 13(8), 192; https://0-doi-org.brum.beds.ac.uk/10.3390/ph13080192
Received: 28 June 2020 / Revised: 3 August 2020 / Accepted: 10 August 2020 / Published: 12 August 2020
(This article belongs to the Special Issue Applications of Medicinal Bioinorganic Chemistry)
In recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative to infectious diseases and, in particular, to cancer. At the basis of these performances of gold, there is the development of new gold-based nanoparticles, characterized by a promising risk/benefit ratio that favors their introduction in clinical trials. Gold nanoparticles appear as attractive elements in nanomedicine, a branch of modern clinical medicine, which combines high selectivity in targeting tumor cells and low toxicity. Thanks to these peculiar characteristics, gold nanoparticles appear as the starting point for the development of new gold-based therapeutic strategies in oncology. Here, the new gold-based therapeutic agents developed in recent years are described, with particular emphasis on the possible applications in clinical practice as anticancer agents, with the aim that their application will give rise to a new golden age in oncology and a breakthrough in the fight against cancer. View Full-Text
Keywords: gold; nanoparticles; oncology gold; nanoparticles; oncology
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MDPI and ACS Style

Gerosa, C.; Crisponi, G.; Nurchi, V.M.; Saba, L.; Cappai, R.; Cau, F.; Faa, G.; Van Eyken, P.; Scartozzi, M.; Floris, G.; Fanni, D. Gold Nanoparticles: A New Golden Era in Oncology? Pharmaceuticals 2020, 13, 192. https://0-doi-org.brum.beds.ac.uk/10.3390/ph13080192

AMA Style

Gerosa C, Crisponi G, Nurchi VM, Saba L, Cappai R, Cau F, Faa G, Van Eyken P, Scartozzi M, Floris G, Fanni D. Gold Nanoparticles: A New Golden Era in Oncology? Pharmaceuticals. 2020; 13(8):192. https://0-doi-org.brum.beds.ac.uk/10.3390/ph13080192

Chicago/Turabian Style

Gerosa, Clara, Guido Crisponi, Valeria M. Nurchi, Luca Saba, Rosita Cappai, Flaviana Cau, Gavino Faa, Peter Van Eyken, Mario Scartozzi, Giuseppe Floris, and Daniela Fanni. 2020. "Gold Nanoparticles: A New Golden Era in Oncology?" Pharmaceuticals 13, no. 8: 192. https://0-doi-org.brum.beds.ac.uk/10.3390/ph13080192

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