The association between health-related quality of life and mortality among hemodialysis patients
Material and methods. This prospective observational study enrolled 183 patients undergoing maintenance hemodialysis. HRQOL was measured annually 2004–2008 using a generic Short Form 36 questionnaire. Physical component summary (PSC) and mental component summary (MSC) scores were calculated. The change of the patient’s HRQOL over time was calculated as a difference between SF-36 scores of the first and the last HRQOL measurements.
Results. The median follow-up was 48 months (range, 1–72 months). Cutoff values for HRQOL predicting mortality for PSC score was ≥35 and for MSC score was ≥45. In the model adjusted for age, sex, dialysis months, creatinine, albumin and hemoglobin levels, mortality risk decreased by 0.96 (95% CI, 0.95–0.99) for 1-point increase in the baseline PSC score and decreased by 0.97 (95% CI, 0.95–0.98) for 1-point increase in the baseline MSC score. A 1-point decline in the PSC score (relative risk, 1.11; 95% CI, 1.008–1.221) and MSC score (relative risk, 1.07; 95% CI, 1.002–1.149) over the period of follow-up were associated with a significant additional increase in mortality.
Conclusions. Both baseline HRQOL and decline of HRQOL are independent predictors of mortality in hemodialysis patients.
Kušleikaitė, N.; Bumblytė, I.A.; Kuzminskis, V.; Vaičiūnienė, R. The association between health-related quality of life and mortality among hemodialysis patients. Medicina 2010, 46, 531. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080076
Kušleikaitė N, Bumblytė IA, Kuzminskis V, Vaičiūnienė R. The association between health-related quality of life and mortality among hemodialysis patients. Medicina. 2010; 46(8):531. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080076Chicago/Turabian Style
Kušleikaitė, Neda, Inga A. Bumblytė, Vytautas Kuzminskis, and Rūta Vaičiūnienė. 2010. "The association between health-related quality of life and mortality among hemodialysis patients" Medicina 46, no. 8: 531. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080076