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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.

Functional Significance of Microsatellite Markers

Genomics and Bioinformatics, Institute of Biology, University of Latvia
Faculty of Medicine, University of Latvia, Latvia
Author to whom correspondence should be addressed.
Received: 13 November 2013 / Accepted: 30 December 2013 / Published: 4 January 2014
The review summarizes literature data on the positive results of association studies between the length of microsatellite repeats and predisposition to pathologies. Actually, the data can be classified according to the localization of the microsatellite: in the gene promoter, in the part of exon 1 coding the signal sequence, in gene introns, in the coding areas of genes, and in 3'-untranslated regions. The functional significance of microsatellite length changes can be evaluated in many cases. The authors came up to the conclusion that further studies on microsatellite associations with diseases remain prospective as they reflect changes in the gene functional activity.
Keywords: microsatellite; human diseases; promoter; intron; exon microsatellite; human diseases; promoter; intron; exon
MDPI and ACS Style

Sjakste, T.; Paramonova, N.; Sjakste, N. Functional Significance of Microsatellite Markers. Medicina 2013, 49, 79.

AMA Style

Sjakste T, Paramonova N, Sjakste N. Functional Significance of Microsatellite Markers. Medicina. 2013; 49(12):79.

Chicago/Turabian Style

Sjakste, Tatjana, Natalia Paramonova, and Nikolajs Sjakste. 2013. "Functional Significance of Microsatellite Markers" Medicina 49, no. 12: 79.

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