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Case Report

Bilateral Optic Neuritis Secondary to Nivolumab Therapy: A Case Report

by 1,* and 2
1
Division of Pediatric Hematology and Oncology, Gülhane Training and Research Hospital, 06300 Ankara, Turkey
2
Division of Pediatric Oncology, Gülhane Training and Research Hospital, 06300 Ankara, Turkey
*
Author to whom correspondence should be addressed.
Received: 31 August 2018 / Revised: 21 October 2018 / Accepted: 31 October 2018 / Published: 6 November 2018
Pediatric glioblastoma multiforme is an uncommon and highly mortal brain cancer. New therapeutic treatments are being intensively investigated by researchers in order to extend the survival of patients. The immune checkpoint inhibitor nivolumab in the treatment of pediatric glioblastoma multiforme is currently under review; it is a human immunoglobulin G4 monoclonal antibody that works against the programmed cell death protein 1 receptor, designed to enhance an immunologic reaction against cancer cells. Herein, we describe the first report of a bilateral optic neuritis induced by nivolumab in a grade 4 glioblastoma multiforme patient. View Full-Text
Keywords: glioblastoma multiforme; nivolumab; optic neuritis glioblastoma multiforme; nivolumab; optic neuritis
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MDPI and ACS Style

Kartal, Ö.; Ataş, E. Bilateral Optic Neuritis Secondary to Nivolumab Therapy: A Case Report. Medicina 2018, 54, 82. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina54050082

AMA Style

Kartal Ö, Ataş E. Bilateral Optic Neuritis Secondary to Nivolumab Therapy: A Case Report. Medicina. 2018; 54(5):82. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina54050082

Chicago/Turabian Style

Kartal, Ömer, and Erman Ataş. 2018. "Bilateral Optic Neuritis Secondary to Nivolumab Therapy: A Case Report" Medicina 54, no. 5: 82. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina54050082

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