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Article

High HOMA-IR Index in Healthcare Shift Workers

1
Occupational Medicine, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy
2
Clinical Pathology and Clinical Molecular Biology Unit, “Garibaldi Centro” Hospital of Catania, 95124 Catania, Italy
3
Occupational Medicine, Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy
4
Occupational Medicine, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60100 Ancona, Italy
*
Author to whom correspondence should be addressed.
Received: 17 January 2019 / Revised: 12 February 2019 / Accepted: 16 May 2019 / Published: 22 May 2019
(This article belongs to the Special Issue Type 2 Diabetes and Insulin Resistance)
Background and objectives: Evidence shows that shift work may be correlated with insulin resistance (IR). Therefore its estimation in clinical and prevention practice is of great significance. A cross-sectional study was performed to examine the Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) Index among healthcare shift workers (HCSW). Materials and Methods: A total of 272 healthcare workers (HCWs) were invited to participate in the study within an occupational surveillance framework, 137 were HCSW while 135 were healthcare non-shift workers (HCNSW). Fasting glucose, insulin, and HOMA-IR Index were evaluated in each participant and correlated with shift workers. Results: Indicators of glucose metabolism were significantly higher in HCSW p < 0.001, and logistic regression analysis confirmed a significant positive association between increased values of HOMA-IR Index and shift workers (p < 0.05). Conclusions: Shift work could be a risk factor in developing insulin resistance and metabolic syndrome. View Full-Text
Keywords: insulin resistance; metabolic syndrome; diabetes; shift work; night work; circadian rhythm; workers insulin resistance; metabolic syndrome; diabetes; shift work; night work; circadian rhythm; workers
MDPI and ACS Style

Ledda, C.; Cinà, D.; Matera, S.; Mucci, N.; Bracci, M.; Rapisarda, V. High HOMA-IR Index in Healthcare Shift Workers. Medicina 2019, 55, 186. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina55050186

AMA Style

Ledda C, Cinà D, Matera S, Mucci N, Bracci M, Rapisarda V. High HOMA-IR Index in Healthcare Shift Workers. Medicina. 2019; 55(5):186. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina55050186

Chicago/Turabian Style

Ledda, Caterina, Diana Cinà, Serena Matera, Nicola Mucci, Massimo Bracci, and Venerando Rapisarda. 2019. "High HOMA-IR Index in Healthcare Shift Workers" Medicina 55, no. 5: 186. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina55050186

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