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High HOMA-IR Index in Healthcare Shift Workers

Occupational Medicine, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy
Clinical Pathology and Clinical Molecular Biology Unit, “Garibaldi Centro” Hospital of Catania, 95124 Catania, Italy
Occupational Medicine, Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy
Occupational Medicine, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60100 Ancona, Italy
Author to whom correspondence should be addressed.
Received: 17 January 2019 / Revised: 12 February 2019 / Accepted: 16 May 2019 / Published: 22 May 2019
(This article belongs to the Special Issue Type 2 Diabetes and Insulin Resistance)
Background and objectives: Evidence shows that shift work may be correlated with insulin resistance (IR). Therefore its estimation in clinical and prevention practice is of great significance. A cross-sectional study was performed to examine the Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) Index among healthcare shift workers (HCSW). Materials and Methods: A total of 272 healthcare workers (HCWs) were invited to participate in the study within an occupational surveillance framework, 137 were HCSW while 135 were healthcare non-shift workers (HCNSW). Fasting glucose, insulin, and HOMA-IR Index were evaluated in each participant and correlated with shift workers. Results: Indicators of glucose metabolism were significantly higher in HCSW p < 0.001, and logistic regression analysis confirmed a significant positive association between increased values of HOMA-IR Index and shift workers (p < 0.05). Conclusions: Shift work could be a risk factor in developing insulin resistance and metabolic syndrome. View Full-Text
Keywords: insulin resistance; metabolic syndrome; diabetes; shift work; night work; circadian rhythm; workers insulin resistance; metabolic syndrome; diabetes; shift work; night work; circadian rhythm; workers
MDPI and ACS Style

Ledda, C.; Cinà, D.; Matera, S.; Mucci, N.; Bracci, M.; Rapisarda, V. High HOMA-IR Index in Healthcare Shift Workers. Medicina 2019, 55, 186.

AMA Style

Ledda C, Cinà D, Matera S, Mucci N, Bracci M, Rapisarda V. High HOMA-IR Index in Healthcare Shift Workers. Medicina. 2019; 55(5):186.

Chicago/Turabian Style

Ledda, Caterina, Diana Cinà, Serena Matera, Nicola Mucci, Massimo Bracci, and Venerando Rapisarda. 2019. "High HOMA-IR Index in Healthcare Shift Workers" Medicina 55, no. 5: 186.

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