Next Article in Journal
Diversity of Nonribosomal Peptide Synthetase Genes in the Microbial Metagenomes of Marine Sponges
Previous Article in Journal
Bioactive Compounds from a Gorgonian Coral Echinomuricea sp. (Plexauridae)
Article

Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine Ostreae concha

1
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
2
Technology Center of China Tobacco Shandong Industrial Corporation, Qingdao 266101, China
*
Authors to whom correspondence should be addressed.
Mar. Drugs 2012, 10(5), 1180-1191; https://0-doi-org.brum.beds.ac.uk/10.3390/md10051180
Received: 5 March 2012 / Revised: 8 May 2012 / Accepted: 10 May 2012 / Published: 23 May 2012
To compare the chemical differences between the medicinal and cultured oyster shells, their chemical profiles were investigated. Using the ultra performance liquid chromatography-electron spraying ionization-mass spectrometry (UPLC-ESI-MS), combined with principal component analysis (PCA) and orthogonal projection to latent structures discriminant analysis (OPLS-DA), the discrimination of the chemical characteristics among the medicinal and cultured oyster shells was established. Moreover, the chemometric analysis revealed some potential key compounds. After a large-scale extraction and isolation, one target key compound was unambiguously identified as caffeine (1) based on extensive spectroscopic data analysis (1D and 2D NMR, MS, and UV) and comparison with literature data. View Full-Text
Keywords: oyster shell; traditional Chinese medicine; chemical profile; principal component analysis; caffeine oyster shell; traditional Chinese medicine; chemical profile; principal component analysis; caffeine
Show Figures

Figure 1

MDPI and ACS Style

Yang, X.; Zhou, S.-L.; Ma, A.-C.; Xu, H.-T.; Guan, H.-S.; Liu, H.-B. Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine Ostreae concha. Mar. Drugs 2012, 10, 1180-1191. https://0-doi-org.brum.beds.ac.uk/10.3390/md10051180

AMA Style

Yang X, Zhou S-L, Ma A-C, Xu H-T, Guan H-S, Liu H-B. Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine Ostreae concha. Marine Drugs. 2012; 10(5):1180-1191. https://0-doi-org.brum.beds.ac.uk/10.3390/md10051180

Chicago/Turabian Style

Yang, Xue, Shi-Lu Zhou, Ai-Cui Ma, Hai-Tao Xu, Hua-Shi Guan, and Hong-Bing Liu. 2012. "Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine Ostreae concha" Marine Drugs 10, no. 5: 1180-1191. https://0-doi-org.brum.beds.ac.uk/10.3390/md10051180

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop