Next Article in Journal
Communication Skills, Problem-Solving Ability, Understanding of Patients’ Conditions, and Nurse’s Perception of Professionalism among Clinical Nurses: A Structural Equation Model Analysis
Next Article in Special Issue
Resistance Training Acutely Impairs Agility and Spike-Specific Performance Measures in Collegiate Female Volleyball Players Returning from the Off-Season
Previous Article in Journal
Disease Perception and Coping with Emotional Distress During COVID-19 Pandemic: A Survey Among Medical Staff
Previous Article in Special Issue
Effect of Body Fat Percentage on Muscle Damage Induced by High-Intensity Eccentric Exercise
Article

Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage

1
Office of Academic Affairs, Konkuk University, Chungju-si 27478, Korea
2
Department of Sport, Health and Rehabilitation, College of Physical Education, Kookmin University, Seoul 02707, Korea
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(13), 4900; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17134900
Received: 19 May 2020 / Revised: 23 June 2020 / Accepted: 1 July 2020 / Published: 7 July 2020
Myostatin A55T genotype is one of the candidates showing inter-individual variation in skeletal muscle phenotypes. The aim of this study was to investigate the effect of the myostatin A55T genotype on markers of muscle damage after eccentric exercise. Forty-eight young, healthy male college students (age = 24.8 ± 2.2 years, height = 176.7 ± 5.3 cm, weight = 73.7 ± 8.3 kg) were enrolled in this study, and muscle damage was induced through 50 reps of maximal eccentric muscle contraction. As markers of muscle damage, maximal isometric strength (MIS), muscle soreness, creatine kinase (CK), and aspartate transaminase (AST) were measured. Myostatin A55T genotypes were classified into homozygous myostatin A55T allele (AA, n = 34, 72%), heterozygous myostatin A55T allele (AT, n = 13, 26%), and homozygous mutant carriers (TT, n = 1, 2%). After eccentric exercise, the subjects with heterozygous for AT showed markedly quicker MIS recovery compared to the AA group (p = 0.042). However, there were no significant variations in muscle soreness (p = 0.379), CK (p = 0.955), and AST (p = 0.706) among the groups. These results suggest that AT in myostatin A55T genotype may be associated with quicker strength recovery following exercise-induced muscle damage. View Full-Text
Keywords: eccentric exercise; genotype; muscle damage; myostatin; strength recovery eccentric exercise; genotype; muscle damage; myostatin; strength recovery
MDPI and ACS Style

Kim, J.; Park, K.; Lee, J. Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage. Int. J. Environ. Res. Public Health 2020, 17, 4900. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17134900

AMA Style

Kim J, Park K, Lee J. Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage. International Journal of Environmental Research and Public Health. 2020; 17(13):4900. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17134900

Chicago/Turabian Style

Kim, Jooyoung, Kwanghoon Park, and Joohyung Lee. 2020. "Myostatin A55T Genotype is Associated with Strength Recovery Following Exercise-Induced Muscle Damage" International Journal of Environmental Research and Public Health 17, no. 13: 4900. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17134900

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop