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Progress in Occupational Asthma

Impact of Air Pollution on Asthma Outcomes

Department of Pulmonology, University Hospital of Nancy, 54395 Nancy, France
Development of Adaptation and Disadvantage, Cardiorespiratory Regulations and Motor Control (EA 3450 DevAH), University of Lorraine, 54395 Nancy, France
Clinic of Clinical Allergy, Medical University, 1000 Sofia, Bulgaria
Medical University Sofia, 1000 Sofia, Bulgaria
Division of Allergy and Immunology, Department of Pediatrics, Federal University of Paraná, Curitiba 80000-000, Brazil
Allergy Unit, Internal Consulting Department, University Hospital “St. George”, 4000 Plovdiv, Bulgaria
Department of Respiratory Medicine, Medical School, Democritus University of Thrace, University General Hospital Dragana, 68100 Alexandroupolis, Greece
Department of Allergology and Internal Medicine, Medical University of Bialystok, 15-037 Bialystok, Poland
Author to whom correspondence should be addressed.
Equal contribution.
Int. J. Environ. Res. Public Health 2020, 17(17), 6212;
Received: 22 July 2020 / Revised: 20 August 2020 / Accepted: 25 August 2020 / Published: 27 August 2020
(This article belongs to the Special Issue Occupational and Environmental Asthma)
Asthma is a chronic respiratory disease characterized by variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air pollution has a negative impact on asthma outcomes in both adult and pediatric populations. The aim of this review is to summarize the current knowledge on the effect of various outdoor and indoor pollutants on asthma outcomes, their burden on its management, as well as to highlight the measures that could result in improved asthma outcomes. Traffic-related air pollution, nitrogen dioxide and second-hand smoking (SHS) exposures represent significant risk factors for asthma development in children. Nevertheless, a causal relation between air pollution and development of adult asthma is not clearly established. Exposure to outdoor pollutants can induce asthma symptoms, exacerbations and decreases in lung function. Active tobacco smoking is associated with poorer asthma control, while exposure to SHS increases the risk of asthma exacerbations, respiratory symptoms and healthcare utilization. Other indoor pollutants such as heating sources and molds can also negatively impact the course of asthma. Global measures, that aim to reduce exposure to air pollutants, are highly needed in order to improve the outcomes and management of adult and pediatric asthma in addition to the existing guidelines. View Full-Text
Keywords: outdoor air pollutants; indoor air pollutants; asthma symptoms; exacerbations; management outdoor air pollutants; indoor air pollutants; asthma symptoms; exacerbations; management
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MDPI and ACS Style

Tiotiu, A.I.; Novakova, P.; Nedeva, D.; Chong-Neto, H.J.; Novakova, S.; Steiropoulos, P.; Kowal, K. Impact of Air Pollution on Asthma Outcomes. Int. J. Environ. Res. Public Health 2020, 17, 6212.

AMA Style

Tiotiu AI, Novakova P, Nedeva D, Chong-Neto HJ, Novakova S, Steiropoulos P, Kowal K. Impact of Air Pollution on Asthma Outcomes. International Journal of Environmental Research and Public Health. 2020; 17(17):6212.

Chicago/Turabian Style

Tiotiu, Angelica I., Plamena Novakova, Denislava Nedeva, Herberto J. Chong-Neto, Silviya Novakova, Paschalis Steiropoulos, and Krzysztof Kowal. 2020. "Impact of Air Pollution on Asthma Outcomes" International Journal of Environmental Research and Public Health 17, no. 17: 6212.

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