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Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training

1
Department of Precision Medicine, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
2
Dermatology Unit, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
3
Department of Mental Health and Preventive, University of Campania Luigi Vanvitelli, 80131 Naples, Italy
4
Department of Pneumology and Tisiology, AO Dei Colli—V. Monaldi, 80130 Naples, Italy
5
Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy
6
Department of Clinical Medicine, Faculty of Medicine at UFPel—Federal University of Pelotas, 1160 Centro, Pelotas, Brazil
*
Author to whom correspondence should be addressed.
These authors contributed equally to the work.
Int. J. Environ. Res. Public Health 2020, 17(3), 839; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17030839
Received: 25 December 2019 / Revised: 16 January 2020 / Accepted: 22 January 2020 / Published: 29 January 2020
(This article belongs to the Special Issue Physical Activity and Elder Health)
Primary cutaneous anaplastic large cell lymphoma (pcALCL) is part of a spectrum of cutaneous CD30+ lymphoproliferative disease that also includes lymphomatoid papulosis. It often occurs in elderly patients, presenting at a median age of 60 years, although it may occur at any age. It is a CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic, or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress, and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. Complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with a solitary lesion. View Full-Text
Keywords: cutaneous lymphoma in the elderly; skin tumors; T-cell lymphomas; sport activity training cutaneous lymphoma in the elderly; skin tumors; T-cell lymphomas; sport activity training
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MDPI and ACS Style

Sica, A.; Vitiello, P.; Ronchi, A.; Casale, B.; Calogero, A.; Sagnelli, E.; Costa Nachtigal, G.; Troiani, T.; Franco, R.; Argenziano, G.; Moscarella, E.; Sagnelli, C. Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training. Int. J. Environ. Res. Public Health 2020, 17, 839. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17030839

AMA Style

Sica A, Vitiello P, Ronchi A, Casale B, Calogero A, Sagnelli E, Costa Nachtigal G, Troiani T, Franco R, Argenziano G, Moscarella E, Sagnelli C. Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training. International Journal of Environmental Research and Public Health. 2020; 17(3):839. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17030839

Chicago/Turabian Style

Sica, Antonello, Paola Vitiello, Andrea Ronchi, Beniamino Casale, Armando Calogero, Evangelista Sagnelli, Gilca Costa Nachtigal, Teresa Troiani, Renato Franco, Giuseppe Argenziano, Elvira Moscarella, and Caterina Sagnelli. 2020. "Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in the Elderly and the Importance of Sport Activity Training" International Journal of Environmental Research and Public Health 17, no. 3: 839. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17030839

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