Next Article in Journal
Geochemical, Mineralogical and Morphological Characterisation of Road Dust and Associated Health Risks
Previous Article in Journal
Environmental UVR Levels and Skin Pigmentation Gene Variants Associated with Folate and Homocysteine Levels in an Elderly Cohort
Article

Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway

by 1, 1,2,*, 2,*, 2 and 2
1
Indoor Environment Engineering Research Center of Fujian Province, College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350118, China
2
School of Engineering, RMIT University, P.O. Box 71, Bundoora, VIC 3083, Australia
*
Authors to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(5), 1556; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17051556
Received: 10 January 2020 / Revised: 25 February 2020 / Accepted: 26 February 2020 / Published: 28 February 2020
This paper presents a computational and experimental study of steady inhalation in a realistic human pharyngeal airway model. To investigate the intricate fluid dynamics inside the pharyngeal airway, the numerical predicted flow patterns are compared with in vitro measurements using Particle Image Velocimetry (PIV) approach. A structured mesh with 1.4 million cells is used with a laminar constant flow rate of 10 L/min. PIV measurements are taken in three sagittal planes which showed flow acceleration after the pharynx bend with high velocities in the posterior pharyngeal wall. Computed velocity profiles are compared with the measurements which showed generally good agreements with over-predicted velocity distributions on the anterior wall side. Secondary flow patterns on cross-sectional slices in the transverse plane revealed vortices posterior of pharynx and a pair of secondary flow vortexes due to the abrupt cross-sectional area increase. Finally, pressure and flow resistance analysis demonstrate that greatest pressure occurs in the superior half of the airway and maximum in-plane pressure variation is observed at the velo-oropharynx junction, which expects to induce a high tendency of airway collapse during inhalation. This study provides insights of the complex fluid dynamics in human pharyngeal airway and can contribute to a reliable approach to assess the probability of flow-induced airway collapse and improve the treatment of obstructive sleep apnea. View Full-Text
Keywords: human pharynx; numerical simulation; in vitro measurements; airway collapse; obstructive sleep apnea human pharynx; numerical simulation; in vitro measurements; airway collapse; obstructive sleep apnea
Show Figures

Figure 1

MDPI and ACS Style

Fan, Y.; Dong, J.; Tian, L.; Inthavong, K.; Tu, J. Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway. Int. J. Environ. Res. Public Health 2020, 17, 1556. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17051556

AMA Style

Fan Y, Dong J, Tian L, Inthavong K, Tu J. Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway. International Journal of Environmental Research and Public Health. 2020; 17(5):1556. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17051556

Chicago/Turabian Style

Fan, Yaming, Jingliang Dong, Lin Tian, Kiao Inthavong, and Jiyuan Tu. 2020. "Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway" International Journal of Environmental Research and Public Health 17, no. 5: 1556. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17051556

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop