Next Article in Journal
The Influence of Occupational Categories on Overall and Domain-Specific Physical Activity and the Association with Chronic Diseases. An Analysis Using the Austrian Health Interview Survey
Next Article in Special Issue
A Miniaturized Microbe-Silicon-Chip Based on Bioluminescent Engineered Escherichia coli for the Evaluation of Water Quality and Safety
Previous Article in Journal
Social Determinants of Diabetes-Related Preventable Hospitalization in Taiwan: A Spatial Analysis
Previous Article in Special Issue
Comprehensive Fungal Community Analysis of House Dust Using Next-Generation Sequencing
Article

Combination of High-Pressure Processing and Freeze-Drying as the Most Effective Techniques in Maintaining Biological Values and Microbiological Safety of Donor Milk

1
Department of Medical Biology, Faculty of Health Sciences, Medical University of Warsaw, 14/16 Litewska St., 00-575 Warsaw, Poland
2
High Pressure Physics, Polish Academy of Science, 29 Sokolowska St., 01-142 Warsaw, Poland
3
Institute of Human Nutrition Sciences, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c St., 02-776 Warsaw, Poland
4
Laboratory of Human Milk and Lactation Research at Regional Human Milk Bank in Holy Family Hospital, Department of Medical Biology, Faculty of Health Sciences, Medical University of Warsaw, 14/16 Litewska St., 00-575 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: María José Benito
Int. J. Environ. Res. Public Health 2021, 18(4), 2147; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18042147
Received: 18 December 2020 / Revised: 2 February 2021 / Accepted: 17 February 2021 / Published: 22 February 2021
Background: Human milk banks have a pivotal role in provide optimal food for those infants who are not fully breastfeed, by allowing human milk from donors to be collected, processed and appropriately distributed. Donor human milk (DHM) is usually preserved by Holder pasteurization, considered to be the gold standard to ensure the microbiology safety and nutritional value of milk. However, as stated by the European Milk Banking Association (EMBA) there is a need to implement the improvement of the operating procedure of human milk banks including preserving and storing techniques. Aim: The purpose of this study was to assess the effectiveness and safety of the selected new combination of methods for preserving donor human milk in comparison with thermal treatment (Holder pasteurization). Methods: We assessed (1) the concentration of bioactive components (insulin, adiponectin, leptin, activity of pancreatic lipase, and hepatocyte growth factor) and (2) microbiological safety in raw and pasteurized, high-pressure processed and lyophilization human breast milk. Results: The combination of two techniques, high-pressure processing and freeze-drying, showed the best potential for preserving the nutritional value of human milk and were evaluated for microbiological safety. Microbiological safety assessment excluded the possibility of using freeze-drying alone for human milk sample preservation. However, it can be used as a method for long-term storage of milk samples, which have previously been preserved via other processes. Conclusion: The results show that high-pressure treatment is the best method for preservation that ensures microbiological safety and biological activity but subsequent freeze-drying allowed long-term storage without loss of properties. View Full-Text
Keywords: safety storage of donor milk; high-pressure processing; freeze-drying safety storage of donor milk; high-pressure processing; freeze-drying
Show Figures

Graphical abstract

MDPI and ACS Style

Jarzynka, S.; Strom, K.; Barbarska, O.; Pawlikowska, E.; Minkiewicz-Zochniak, A.; Rosiak, E.; Oledzka, G.; Wesolowska, A. Combination of High-Pressure Processing and Freeze-Drying as the Most Effective Techniques in Maintaining Biological Values and Microbiological Safety of Donor Milk. Int. J. Environ. Res. Public Health 2021, 18, 2147. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18042147

AMA Style

Jarzynka S, Strom K, Barbarska O, Pawlikowska E, Minkiewicz-Zochniak A, Rosiak E, Oledzka G, Wesolowska A. Combination of High-Pressure Processing and Freeze-Drying as the Most Effective Techniques in Maintaining Biological Values and Microbiological Safety of Donor Milk. International Journal of Environmental Research and Public Health. 2021; 18(4):2147. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18042147

Chicago/Turabian Style

Jarzynka, Sylwia, Kamila Strom, Olga Barbarska, Emilia Pawlikowska, Anna Minkiewicz-Zochniak, Elzbieta Rosiak, Gabriela Oledzka, and Aleksandra Wesolowska. 2021. "Combination of High-Pressure Processing and Freeze-Drying as the Most Effective Techniques in Maintaining Biological Values and Microbiological Safety of Donor Milk" International Journal of Environmental Research and Public Health 18, no. 4: 2147. https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18042147

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop