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Case Report

Resolution of Severe Oncogenic Hypophosphatemic Osteomalacia after Resection of a Deeply Located Soft-Tissue Tumour

by
A. R. M. Radaideh
1,
D. Jaradat
2,
M. M. Abu-Kalaf
3 and
M. K. Nusier
4,*
1
Departments of Medicine, Prince Basma Teaching Hospital, Ministry of Health, Irbid, Jordan
2
Departments of Radiology, Prince Basma Teaching Hospital, Ministry of Health, Irbid, Jordan
3
Department of Surgery, Jordan University, School of Medicine, Amman, Jordan
4
MedLabs Consultancy Group, Amman 11183, Jordan
*
Author to whom correspondence should be addressed.
Submission received: 3 June 2009 / Revised: 8 July 2009 / Accepted: 5 August 2009 / Published: 1 September 2009

Abstract

Oncogenic osteomalacia is a rare metabolic bone disease characterized by phosphate leakage from the kidney and subsequent hypophosphatemia. It is caused by a phosphaturic factor produced by certain tumours. Removal of such tumours can completely cure the condition. Here, we report the case of a patient who was crippled with oncogenic osteomalacia. Extensive study revealed a tumour deeply located in the pelvis; removal of the tumour resulted in complete recovery. The tumour was identified as a mesenchymal tumour (mixed connective-tissue variant). The diagnostic evaluation, differential diagnosis, and treatment are discussed.
Keywords: oncogenic osteomalacia; mesenchymal tumour; mixed connective-tissue tumour; 1,25-dihydroxycholecalciferol; rickets; hypophosphatemia; fibroblast growth factor 23 oncogenic osteomalacia; mesenchymal tumour; mixed connective-tissue tumour; 1,25-dihydroxycholecalciferol; rickets; hypophosphatemia; fibroblast growth factor 23

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MDPI and ACS Style

Radaideh, A.R.M.; Jaradat, D.; Abu-Kalaf, M.M.; Nusier, M.K. Resolution of Severe Oncogenic Hypophosphatemic Osteomalacia after Resection of a Deeply Located Soft-Tissue Tumour. Curr. Oncol. 2009, 16, 87-90. https://0-doi-org.brum.beds.ac.uk/10.3747/co.v16i5.412

AMA Style

Radaideh ARM, Jaradat D, Abu-Kalaf MM, Nusier MK. Resolution of Severe Oncogenic Hypophosphatemic Osteomalacia after Resection of a Deeply Located Soft-Tissue Tumour. Current Oncology. 2009; 16(5):87-90. https://0-doi-org.brum.beds.ac.uk/10.3747/co.v16i5.412

Chicago/Turabian Style

Radaideh, A. R. M., D. Jaradat, M. M. Abu-Kalaf, and M. K. Nusier. 2009. "Resolution of Severe Oncogenic Hypophosphatemic Osteomalacia after Resection of a Deeply Located Soft-Tissue Tumour" Current Oncology 16, no. 5: 87-90. https://0-doi-org.brum.beds.ac.uk/10.3747/co.v16i5.412

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