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Article

First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region

1
Centre d’Infectiologie Charles Mérieux du Mali, BPE2283 Bamako, Mali
2
Bundeswehr Institute of Microbiology, D-80937 Munich, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this study.
Received: 16 October 2020 / Revised: 29 October 2020 / Accepted: 29 October 2020 / Published: 2 November 2020
(This article belongs to the Collection Coronaviruses)
We are currently facing a pandemic of COVID-19, caused by a spillover from an animal-originating coronavirus to humans occurring in the Wuhan region of China in December 2019. From China, the virus has spread to 188 countries and regions worldwide, reaching the Sahel region on 2 March 2020. Since whole genome sequencing (WGS) data is very crucial to understand the spreading dynamics of the ongoing pandemic, but only limited sequencing data is available from the Sahel region to date, we have focused our efforts on generating the first Malian sequencing data available. Screening 217 Malian patient samples for the presence of SARS-CoV-2 resulted in 38 positive isolates, from which 21 whole genome sequences were generated. Our analysis shows that both the early A (19B) and the later observed B (20A/C) clade are present in Mali, indicating multiple and independent introductions of SARS-CoV-2 to the Sahel region. View Full-Text
Keywords: SARS-CoV-2; phylogenetic analysis; Mali SARS-CoV-2; phylogenetic analysis; Mali
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MDPI and ACS Style

Kouriba, B.; Dürr, A.; Rehn, A.; Sangaré, A.K.; Traoré, B.Y.; Bestehorn-Willmann, M.S.; Ouedraogo, J.; Heitzer, A.; Sogodogo, E.; Maiga, A.; Walter, M.C.; Zimmermann, F.; Wölfel, R.; Antwerpen, M.H. First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region. Viruses 2020, 12, 1251. https://0-doi-org.brum.beds.ac.uk/10.3390/v12111251

AMA Style

Kouriba B, Dürr A, Rehn A, Sangaré AK, Traoré BY, Bestehorn-Willmann MS, Ouedraogo J, Heitzer A, Sogodogo E, Maiga A, Walter MC, Zimmermann F, Wölfel R, Antwerpen MH. First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region. Viruses. 2020; 12(11):1251. https://0-doi-org.brum.beds.ac.uk/10.3390/v12111251

Chicago/Turabian Style

Kouriba, Bourema; Dürr, Angela; Rehn, Alexandra; Sangaré, Abdoul K.; Traoré, Brehima Y.; Bestehorn-Willmann, Malena S.; Ouedraogo, Judicael; Heitzer, Asli; Sogodogo, Elisabeth; Maiga, Abderrhamane; Walter, Mathias C.; Zimmermann, Fee; Wölfel, Roman; Antwerpen, Markus H. 2020. "First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region" Viruses 12, no. 11: 1251. https://0-doi-org.brum.beds.ac.uk/10.3390/v12111251

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