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Commentary

Phages Needed against Resistant Bacteria

1
Institute for Medical Microbiology, University Zurich, Gloriastr 30, CH-8006 Zurich, Switzerland
2
Max-Planck-Institute for Molecular Genetics, Ihnestr 63-73, D-14195 Berlin, Germany
Received: 9 June 2020 / Revised: 6 July 2020 / Accepted: 7 July 2020 / Published: 10 July 2020
(This article belongs to the Special Issue Novel Concepts in Virology)
Phages have been known for more than 100 years. They have been applied to numerous infectious diseases and have proved to be effective in many cases. However, they have been neglected due to the era of antibiotics. With the increase of antibiotic-resistant microorganisms, we need additional therapies. Whether or not phages can fulfill this expectation needs to be verified and tested according to the state-of-the-art of international regulations. These regulations fail, however, with respect to GMP production of phages. Phages are biologicals, not chemical compounds, which cannot be produced under GMP regulations. This needs to be urgently changed to allow progress to determine how phages can enter routine clinical settings. View Full-Text
Keywords: phage therapy; multidrug-resistant bacteria; case reports; regulation; probiotics phage therapy; multidrug-resistant bacteria; case reports; regulation; probiotics
MDPI and ACS Style

Moelling, K. Phages Needed against Resistant Bacteria. Viruses 2020, 12, 743. https://0-doi-org.brum.beds.ac.uk/10.3390/v12070743

AMA Style

Moelling K. Phages Needed against Resistant Bacteria. Viruses. 2020; 12(7):743. https://0-doi-org.brum.beds.ac.uk/10.3390/v12070743

Chicago/Turabian Style

Moelling, Karin. 2020. "Phages Needed against Resistant Bacteria" Viruses 12, no. 7: 743. https://0-doi-org.brum.beds.ac.uk/10.3390/v12070743

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