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Review

From A to m6A: The Emerging Viral Epitranscriptome

Virology Unit, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Alfredo Castello
Received: 30 April 2021 / Revised: 21 May 2021 / Accepted: 23 May 2021 / Published: 1 June 2021
There are over 100 different chemical RNA modifications, collectively known as the epitranscriptome. N6-methyladenosine (m6A) is the most commonly found internal RNA modification in cellular mRNAs where it plays important roles in the regulation of the mRNA structure, stability, translation and nuclear export. This modification is also found in viral RNA genomes and in viral mRNAs derived from both RNA and DNA viruses. A growing body of evidence indicates that m6A modifications play important roles in regulating viral replication by interacting with the cellular m6A machinery. In this review, we will exhaustively detail the current knowledge on m6A modification, with an emphasis on its function in virus biology. View Full-Text
Keywords: m6A; viral infection; epitranscriptomics; RNA modification m6A; viral infection; epitranscriptomics; RNA modification
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MDPI and ACS Style

Baquero-Perez, B.; Geers, D.; Díez, J. From A to m6A: The Emerging Viral Epitranscriptome. Viruses 2021, 13, 1049. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061049

AMA Style

Baquero-Perez B, Geers D, Díez J. From A to m6A: The Emerging Viral Epitranscriptome. Viruses. 2021; 13(6):1049. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061049

Chicago/Turabian Style

Baquero-Perez, Belinda, Daryl Geers, and Juana Díez. 2021. "From A to m6A: The Emerging Viral Epitranscriptome" Viruses 13, no. 6: 1049. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061049

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