Next Article in Journal
Retroviral Infections in Sheep and Goats: Small Ruminant Lentiviruses and Host Interaction
Next Article in Special Issue
Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins
Previous Article in Journal
A Polytropic Caprine Arthritis Encephalitis Virus Promoter Isolated from Multiple Tissues from a Sheep with Multisystemic Lentivirus-Associated Inflammatory Disease
Previous Article in Special Issue
Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection

Viral Subversion of the Nuclear Pore Complex

by 1,2,* and 1,2,*
Lady Davis Institute at the Jewish General Hospital, McGill University, Montreal, Quebec H3T 1E2, Canada
Department of Medicine, McGill University, Montreal, Quebec H3A 2B4, Canada
Authors to whom correspondence should be addressed.
Received: 3 June 2013 / Revised: 29 July 2013 / Accepted: 8 August 2013 / Published: 16 August 2013
(This article belongs to the Special Issue Viral Nuclear Import)
The nuclear pore complex (NPC) acts as a selective barrier between the nucleus and the cytoplasm and is responsible for mediating communication by regulating the transport of RNA and proteins. Numerous viral pathogens have evolved different mechanisms to hijack the NPC in order to regulate trafficking of viral proteins, genomes and even capsids into and out of the nucleus thus promoting virus replication. The present review examines the different strategies and the specific nucleoporins utilized during viral infections as a means of promoting their life cycle and inhibiting host viral defenses. View Full-Text
Keywords: viruses; nuclear pore complex; nucleoporins; nucleocytoplasmic transport viruses; nuclear pore complex; nucleoporins; nucleocytoplasmic transport
Show Figures

Figure 1

MDPI and ACS Style

Le Sage, V.; Mouland, A.J. Viral Subversion of the Nuclear Pore Complex. Viruses 2013, 5, 2019-2042.

AMA Style

Le Sage V, Mouland AJ. Viral Subversion of the Nuclear Pore Complex. Viruses. 2013; 5(8):2019-2042.

Chicago/Turabian Style

Le Sage, Valerie, and Andrew J. Mouland 2013. "Viral Subversion of the Nuclear Pore Complex" Viruses 5, no. 8: 2019-2042.

Find Other Styles

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Back to TopTop