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Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes

Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Nottingham NG7 2RD, UK
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia
Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
Author to whom correspondence should be addressed.
Received: 7 May 2019 / Revised: 14 May 2019 / Accepted: 16 May 2019 / Published: 18 May 2019
(This article belongs to the Special Issue The Role of Diet on Insulin Sensitivity)
Few evaluations of interventions to delay or prevent type 2 diabetes mellitus (T2DM) in Saudi Arabia (SA) have been undertaken. The present study evaluates the impact of a 6-month intensive lifestyle modification intervention delivered in primary care. Females from SA with prediabetes, aged 18–55 years, were recruited with 190 participants eligible following screening and randomly allocated to receive a 3-month one-on-one, intensive lifestyle modification (intervention group (IG) n = 95) or standard guidance (control group (CG) n = 95). Participants completed questionnaires including demographic, dietary and physical activity data. Blood samples were collected at baseline, 3 and 6 months. A total of 123 (74 IG (age 40.6 ± 9.8 years; body mass index (BMI) 31.2 ± 7.0 kg/m2) and 49 CG (age 40.6 ± 12.7 years; BMI 32.3 ± 5.4 kg/m2)) participants completed the study. After 6 months, haemoglobin A1c (HbA1c; primary endpoint) significantly improved in the IG than CG completers in between-group comparisons (p < 0.001). Comparison between groups showed significant improvements in overall energy intake, total and high density lipoprotein (HDL)-cholesterol in favour of IG (p-values < 0.001, 0.04 and <0.001, respectively). BMI and weight change were not clinically significant in between group comparisons. A 6-month, intense one-on-one intervention in lifestyle modification significantly improves glycaemic and cardio metabolic profile of females living in SA with pre-diabetes delivered in a primary care setting. Longer duration studies, using the same intervention, may determine whether a meaningful weight loss secondary to improved diet can be achieved. View Full-Text
Keywords: pre-diabetes; lifestyle; Arabs; intervention pre-diabetes; lifestyle; Arabs; intervention
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MDPI and ACS Style

Al-Hamdan, R.; Avery, A.; Salter, A.; Al-Disi, D.; Al-Daghri, N.M.; McCullough, F. Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes. Nutrients 2019, 11, 1113.

AMA Style

Al-Hamdan R, Avery A, Salter A, Al-Disi D, Al-Daghri NM, McCullough F. Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes. Nutrients. 2019; 11(5):1113.

Chicago/Turabian Style

Al-Hamdan, Rasha, Amanda Avery, Andrew Salter, Dara Al-Disi, Nasser M. Al-Daghri, and Fiona McCullough. 2019. "Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes" Nutrients 11, no. 5: 1113.

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