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Review

The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer

1
Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Málaga, Andalucía Tech, 29071 Málaga, Spain
2
IBIMA (Biomedical Research Institute of Málaga), 29071 Málaga, Spain
3
Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, 3000 Leuven, Belgium
4
Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium
5
CIBER of Rare Diseases, Group U741 (CB06/07/0046), 29071 Málaga, Spain
*
Authors to whom correspondence should be addressed.
Received: 19 August 2019 / Revised: 19 August 2019 / Accepted: 25 August 2019 / Published: 31 August 2019
(This article belongs to the Special Issue Impact of adherence to the Mediterranean diet on health)
Diet-based chemoprevention of cancer has emerged as an interesting approach to evade the disease or even target its early phases, reducing its incidence or slowing down tumor progression. In its basis in the essential role of angiogenesis for tumor growth and metastasis, angioprevention proposes the use of inhibitors of angiogenesis in cancer prevention. The anti-angiogenic potential exhibited by many natural compounds contained in many Mediterranean diet constituents makes this dietary pattern especially interesting as a source of chemopreventive agents, defined within the angioprevention strategy. In this review, we focus on natural bioactive compounds derived from the main foods included in the Mediterranean diet that display anti-angiogenic activity, as well as their possible use as angiopreventive agents. View Full-Text
Keywords: angiogenesis; cancer; chemoprevention; angioprevention; Mediterranean diet; bioactive compounds angiogenesis; cancer; chemoprevention; angioprevention; Mediterranean diet; bioactive compounds
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MDPI and ACS Style

Martínez-Poveda, B.; Torres-Vargas, J.A.; Ocaña, M.d.C.; García-Caballero, M.; Medina, M.Á.; Quesada, A.R. The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer. Nutrients 2019, 11, 2036. https://0-doi-org.brum.beds.ac.uk/10.3390/nu11092036

AMA Style

Martínez-Poveda B, Torres-Vargas JA, Ocaña MdC, García-Caballero M, Medina MÁ, Quesada AR. The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer. Nutrients. 2019; 11(9):2036. https://0-doi-org.brum.beds.ac.uk/10.3390/nu11092036

Chicago/Turabian Style

Martínez-Poveda, Beatriz, José A. Torres-Vargas, María d.C. Ocaña, Melissa García-Caballero, Miguel Á. Medina, and Ana R. Quesada 2019. "The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer" Nutrients 11, no. 9: 2036. https://0-doi-org.brum.beds.ac.uk/10.3390/nu11092036

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