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Complementary Feeding in Preterm Infants: Where Do We Stand?
Review

Complementary Feeding in Preterm Infants: A Systematic Review

1
Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Neonatal Intensive Care Unit, 20122 Milan, Italy
2
Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy
3
Neonatology and Neonatal Intensive Care Unit, University of Turin, 10126 Turin, Italy
4
Neonatal Intensive Care Unit, AOU Bologna, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy
*
Author to whom correspondence should be addressed.
Members of the Study Group on Neonatal Nutrition and Gastroenterology—Italian Society of Neonatology: Arianna Aceti, Mariella Baldassarre, Elisa Civardi, Luigi Corvaglia, Alessandra Coscia, Francesco Cresi, Luigi Gagliardi, Laura Ilardi, Nadia Liotto, Luca Maggio, Elena Maggiora, Anna Orsi, Guglielmo Salvatori.
Received: 27 May 2020 / Revised: 16 June 2020 / Accepted: 17 June 2020 / Published: 20 June 2020
(This article belongs to the Special Issue Complementary Feeding in Preterm Newborns)
Background: This systematic review summarizes available literature regarding complementary feeding (CF) in preterm infants, with or without comorbidities that may interfere with oral functions. Methods: A literature search was conducted in PubMed and the Cochrane Library. Studies relating to preterm infants (gestational age <37 weeks) were included in the analysis. Retrieved papers were categorized according to their main topic: CF timing and quality; clinical outcome; recommendations; strategies in infants with oral dysfunction. Results: The literature search in PubMed retrieved 6295 papers. Forty met inclusion criteria. The Cochrane search identified four additional study protocols, two related to studies included among PubMed search results, and two ongoing trials. Moreover, among 112 papers dealing with oral feeding, four aiming at managing CF in preterm infants with oral dysfunctions were identified. Conclusions: The available literature does not provide specific guidelines on the management of CF in preterm infants, who are generally weaned earlier than term infants. There is a paucity of data regarding the relationship between CF and growth/quality of growth and health outcomes in preterm infants. It could be suggested to start CF between five and eight months of chronological age if infants have reached three months corrected age and if they have acquired the necessary developmental skills. An individualized multidisciplinary intervention is advisable for preterm infants with oral dysfunctions. View Full-Text
Keywords: complementary feeding; weaning; preterm infants; oral dysfunction complementary feeding; weaning; preterm infants; oral dysfunction
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MDPI and ACS Style

Liotto, N.; Cresi, F.; Beghetti, I.; Roggero, P.; Menis, C.; Corvaglia, L.; Mosca, F.; Aceti, A.; on behalf of the Study Group on Neonatal Nutrition and Gastroenterology—Italian Society of Neonatology. Complementary Feeding in Preterm Infants: A Systematic Review. Nutrients 2020, 12, 1843. https://0-doi-org.brum.beds.ac.uk/10.3390/nu12061843

AMA Style

Liotto N, Cresi F, Beghetti I, Roggero P, Menis C, Corvaglia L, Mosca F, Aceti A, on behalf of the Study Group on Neonatal Nutrition and Gastroenterology—Italian Society of Neonatology. Complementary Feeding in Preterm Infants: A Systematic Review. Nutrients. 2020; 12(6):1843. https://0-doi-org.brum.beds.ac.uk/10.3390/nu12061843

Chicago/Turabian Style

Liotto, Nadia, Francesco Cresi, Isadora Beghetti, Paola Roggero, Camilla Menis, Luigi Corvaglia, Fabio Mosca, Arianna Aceti, and on behalf of the Study Group on Neonatal Nutrition and Gastroenterology—Italian Society of Neonatology. 2020. "Complementary Feeding in Preterm Infants: A Systematic Review" Nutrients 12, no. 6: 1843. https://0-doi-org.brum.beds.ac.uk/10.3390/nu12061843

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