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Article

Aflatoxin M1 Determination in Infant Formulae Distributed in Monterrey, Mexico

1
Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León, Monterrey 64460, N.L.; Mexico
2
CONACYT–Centro de Investigación en Biotecnología Aplicada-IPN, Ex-Hacienda San Juan Molino Carretera Estatal Tecuexcomac, Tlaxcala 90700, Mexico
3
Centre d’Innovació, Recerca i Transferència en Tecnologia dels Aliments (CIRTTA), TECNIO-UAB, MALTA-Consolider Team, Departament de Ciència Animal i dels Aliments, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
*
Author to whom correspondence should be addressed.
Received: 27 December 2019 / Revised: 22 January 2020 / Accepted: 31 January 2020 / Published: 4 February 2020
(This article belongs to the Special Issue Mycotoxins in Feed and Food Chain: Present Status and Future Concerns)
The occurrence of aflatoxin M1 (AFM1) in infant formulae commercialized in the metropolitan area of Monterrey (Nuevo León, Mexico) was determined by using immunoaffinity column clean-up followed by HPLC determination with fluorimetric detection. For this, 55 infant formula powders were classified in two groups, starter (49 samples) and follow-on (6 samples) formulae. Eleven of the evaluated samples (20%) presented values above the permissible limit set by the European Union for infant formulae (25 ng/L), ranging from 40 to 450 ng/L. The estimated daily intake (EDI) for AFM1 was determined employing the average body weight (bw) of the groups of age in the ranges of 0–6 and 6–12 months, and 1–2 years. The results evidenced high intake values, ranging from 1.56 to 14 ng/kg bw/day, depending on the group. Finally, with the EDI value, the carcinogenic risk index was determined, presenting a high risk for all the evaluated groups. Based on these results, it is a necessary extra effort by the regulatory agencies to reduce the AFM1 presence in infant formulae consumed in Mexico. View Full-Text
Keywords: AMF1; infant formulae; estimated daily intake; carcinogenic risk index; Monterrey (Mexico) AMF1; infant formulae; estimated daily intake; carcinogenic risk index; Monterrey (Mexico)
MDPI and ACS Style

Quevedo-Garza, P.A.; Amador-Espejo, G.G.; Salas-García, R.; Ramos-Peña, E.G.; Trujillo, A.-J. Aflatoxin M1 Determination in Infant Formulae Distributed in Monterrey, Mexico. Toxins 2020, 12, 100. https://0-doi-org.brum.beds.ac.uk/10.3390/toxins12020100

AMA Style

Quevedo-Garza PA, Amador-Espejo GG, Salas-García R, Ramos-Peña EG, Trujillo A-J. Aflatoxin M1 Determination in Infant Formulae Distributed in Monterrey, Mexico. Toxins. 2020; 12(2):100. https://0-doi-org.brum.beds.ac.uk/10.3390/toxins12020100

Chicago/Turabian Style

Quevedo-Garza, Patricia A., Genaro G. Amador-Espejo, Rogelio Salas-García, Esteban G. Ramos-Peña, and Antonio-José Trujillo. 2020. "Aflatoxin M1 Determination in Infant Formulae Distributed in Monterrey, Mexico" Toxins 12, no. 2: 100. https://0-doi-org.brum.beds.ac.uk/10.3390/toxins12020100

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