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Review

Evolution of CG Methylation Maintenance Machinery in Plants

1
IPS, University of Bern, 3013 Bern, Switzerland
2
CIRAD, DIADE, IRD, University of Montpellier, 34393 Montpellier, France
*
Authors to whom correspondence should be addressed.
Academic Editors: Clara Bourbousse and Sandra Fonseca
Received: 19 July 2021 / Revised: 6 September 2021 / Accepted: 10 September 2021 / Published: 14 September 2021
(This article belongs to the Special Issue Mechanisms of Plant Epigenome Dynamics)
Cytosine methylation is an epigenetic mark present in most eukaryotic genomes that contributes to the regulation of gene expression and the maintenance of genome stability. DNA methylation mostly occurs at CG sequences, where it is initially deposited by de novo DNA methyltransferases and propagated by maintenance DNA methyltransferases (DNMT) during DNA replication. In this review, we first summarize the mechanisms maintaining CG methylation in mammals that involve the DNA Methyltransferase 1 (DNMT1) enzyme and its cofactor, UHRF1 (Ubiquitin-like with PHD and RING Finger domain 1). We then discuss the evolutionary conservation and diversification of these two core factors in the plant kingdom and speculate on potential functions of novel homologues typically observed in land plants but not in mammals. View Full-Text
Keywords: DNA methylation; DNA METHYLTRANSFERASE 1; MET1; epigenetics; plant DNA methylation; DNA METHYLTRANSFERASE 1; MET1; epigenetics; plant
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MDPI and ACS Style

Tirot, L.; Jullien, P.E.; Ingouff, M. Evolution of CG Methylation Maintenance Machinery in Plants. Epigenomes 2021, 5, 19. https://0-doi-org.brum.beds.ac.uk/10.3390/epigenomes5030019

AMA Style

Tirot L, Jullien PE, Ingouff M. Evolution of CG Methylation Maintenance Machinery in Plants. Epigenomes. 2021; 5(3):19. https://0-doi-org.brum.beds.ac.uk/10.3390/epigenomes5030019

Chicago/Turabian Style

Tirot, Louis, Pauline E. Jullien, and Mathieu Ingouff. 2021. "Evolution of CG Methylation Maintenance Machinery in Plants" Epigenomes 5, no. 3: 19. https://0-doi-org.brum.beds.ac.uk/10.3390/epigenomes5030019

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