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Review

Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue

by 1,2,3, 3 and 1,2,4,5,*
1
Institut du Savoir Montfort, 1E103, 713 Montreal Road, Ottawa, ON K1K 0T2, Canada
2
Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1N 6N5, Canada
3
Clinical Diabetes and Metabolism, Department of Medical Sciences, Uppsala University, 752 36 Uppsala, Sweden
4
School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada
5
Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada
*
Author to whom correspondence should be addressed.
Academic Editor: Frank Gobas
Received: 20 January 2021 / Revised: 12 March 2021 / Accepted: 2 April 2021 / Published: 19 April 2021
(This article belongs to the Special Issue Effect of Environmental Pollutants on Metabolic Defects)
Bisphenol A (BPA) and bisphenol S (BPS) are environmental contaminants that have been associated with the development of insulin resistance and type 2 diabetes (T2D). Two organs that are often implicated in the development of insulin resistance are the skeletal muscle and the adipose tissue, however, seldom studies have investigated the effects of bisphenols on their metabolism. In this review we discuss metabolic perturbations that occur in both the skeletal muscle and adipose tissue affected with insulin resistance, and how exposure to BPA or BPS has been linked to these changes. Furthermore, we highlight the possible effects of BPA on the cross-talk between the skeletal muscle and adipose tissue. View Full-Text
Keywords: BPA; BPS; skeletal muscle; adipose tissue; insulin resistance; type 2 diabetes BPA; BPS; skeletal muscle; adipose tissue; insulin resistance; type 2 diabetes
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MDPI and ACS Style

Ahmed, F.; Pereira, M.J.; Aguer, C. Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue. Environments 2021, 8, 35. https://0-doi-org.brum.beds.ac.uk/10.3390/environments8040035

AMA Style

Ahmed F, Pereira MJ, Aguer C. Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue. Environments. 2021; 8(4):35. https://0-doi-org.brum.beds.ac.uk/10.3390/environments8040035

Chicago/Turabian Style

Ahmed, Fozia, Maria J. Pereira, and Céline Aguer. 2021. "Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue" Environments 8, no. 4: 35. https://0-doi-org.brum.beds.ac.uk/10.3390/environments8040035

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