Brain Sci., Volume 11, Issue 1 (January 2021) – 127 articles
Cover Story (view full-size image): Multiple sclerosis (MS) is a neurodegenerative disease that causes lesion formation and tissue loss or atrophy in the brain. Cognitive and motor challenges are commonly observed in people with MS. Reduced speed of information processing is typically the first sign of cognitive involvement, which in turn broadly affects other cognitive processes including attention, executive function, and memory. The Attention Network Test—Interactions can measure the efficiency of 3 distinct attentional processes—alerting, orienting, and executive control. In this study, we measured attentional efficiencies and gray matter morphometry in a sample of young adults (18–35 years) with relatively mild MS severity. We show that thickness and volume changes in specific gray matter regions correlate with attentional efficiency even in the absence of widespread atrophy. View this paper
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