Next Article in Journal
Mechanical Consequences of Dynamically Loaded NiTi Wires under Typical Actuator Conditions in Rehabilitation and Neuroscience
Next Article in Special Issue
Analysis of Chemisorbed Tribo-Film for Ceramic-on-Ceramic Hip Joint Prostheses by Raman Spectroscopy
Previous Article in Journal
Biocompatibility and Biological Corrosion Resistance of Ti–39Nb–6Zr+0.45Al Implant Alloy
Previous Article in Special Issue
Biocompatibility of α-Al2O3 Ceramic Substrates with Human Neural Precursor Cells
Article

Micro-Nano Surface Characterization and Bioactivity of a Calcium Phosphate-Incorporated Titanium Implant Surface

1
Laboratory of Biomaterials and Oral Pathology, School of Dentistry, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy
2
Endodontic Clinical Section, School of Dentistry, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy
3
Department of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance, University of Modena and Reggio Emilia, 41121 Modena, Italy
4
Biochemistry Unit, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy
*
Author to whom correspondence should be addressed.
J. Funct. Biomater. 2021, 12(1), 3; https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010003
Received: 28 November 2020 / Revised: 24 December 2020 / Accepted: 4 January 2021 / Published: 7 January 2021
(This article belongs to the Special Issue Advanced Bioceramics)
The surface topography of dental implants and micro-nano surface characterization have gained particular interest for the improvement of the osseointegration phases. The aim of this study was to evaluate the surface micro-nanomorphology and bioactivity (apatite forming ability) of Ossean® surface, a resorbable blast medium (RBM) blasted surface further processed through the incorporation of a low amount of calcium phosphate. The implants were analyzed using environmental scanning electronic microscopy (ESEM), connected to Energy dispersive X-ray spectroscopy (EDX), field emission gun SEM-EDX (SEM-FEG) micro-Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) before and after immersion in weekly refreshed Hank’s balanced salt solution (HBSS) for 28 days. The analysis of the samples before immersion showed a moderately rough surface, with micropits and microgrooves distributed on all of the surface; EDX microanalysis revealed the constitutional elements of the implant surface, namely titanium (Ti), aluminum (Al) and vanadium (V). Limited traces of calcium (Ca) and phosphorous (P) were detected, attributable to the incorporated calcium phosphate. No traces of calcium phosphate phases were detected by micro-Raman spectroscopy. ESEM analysis of the implant aged in HBSS for 28 days revealed a significantly different surface, compared to the implant before immersion. At original magnifications <2000×, a homogeneous mineral layer was present on all the surface, covering all the pits and microgrooves. At original magnifications ≥10,000×, the mineral layer revealed the presence of small microspherulites. The structure of these spherulites (approx. 2 µm diameter) was observed in nanoimmersion mode revealing a regular shape with a hairy-like contour. Micro-Raman analysis showed the presence of B-type carbonated apatite on the implant surface, which was further confirmed by XPS analysis. This implant showed a micro-nano-textured surface supporting the formation of a biocompatible apatite when immersed in HBSS. These properties may likely favor bone anchorage and healing by stimulation of mineralizing cells. View Full-Text
Keywords: dental implant surfaces; ESEM-EDX; SEM-FEG; bioactivity; micro-Raman spectroscopy dental implant surfaces; ESEM-EDX; SEM-FEG; bioactivity; micro-Raman spectroscopy
Show Figures

Figure 1

MDPI and ACS Style

Zamparini, F.; Prati, C.; Generali, L.; Spinelli, A.; Taddei, P.; Gandolfi, M.G. Micro-Nano Surface Characterization and Bioactivity of a Calcium Phosphate-Incorporated Titanium Implant Surface. J. Funct. Biomater. 2021, 12, 3. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010003

AMA Style

Zamparini F, Prati C, Generali L, Spinelli A, Taddei P, Gandolfi MG. Micro-Nano Surface Characterization and Bioactivity of a Calcium Phosphate-Incorporated Titanium Implant Surface. Journal of Functional Biomaterials. 2021; 12(1):3. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010003

Chicago/Turabian Style

Zamparini, Fausto, Carlo Prati, Luigi Generali, Andrea Spinelli, Paola Taddei, and Maria G. Gandolfi 2021. "Micro-Nano Surface Characterization and Bioactivity of a Calcium Phosphate-Incorporated Titanium Implant Surface" Journal of Functional Biomaterials 12, no. 1: 3. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010003

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop