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Article

Drastic Reduction of Bacterial, Fungal and Viral Pathogen Titers by Cuprous Oxide Impregnated Medical Textiles

1
Cupron Scientific Ltd., Hasadnaot 10, Herzliya 4672837, Israel
2
Cupron Inc., 4329 November Avenue, Richmond, VA 23231, USA
*
Author to whom correspondence should be addressed.
J. Funct. Biomater. 2021, 12(1), 9; https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010009
Received: 22 December 2020 / Revised: 22 January 2021 / Accepted: 27 January 2021 / Published: 1 February 2021
Hospital patients and personnel are at risk of nosocomial viral infections, as clearly manifested during the COVID-19 pandemic. Transmission of respiratory viral pathogens can occur through contaminated surfaces, including from medical textiles. Copper has potent biocidal properties, and cuprous oxide impregnated medical textiles (CMT) reduce hospital-acquired bacterial infections. In the current study we confirm the antimicrobial properties of CMT and determine their capacity to reduce infectious titres of human coronavirus (HCoV-229E) in an independent laboratory. The antibacterial and antiviral activities of the CMT were determined according to AATCC TM100-2019 and ISO 18184:2019 standards, respectively. The CMT reduced by 4 logs the viable titers of MRSA, Klebsiella pneumoniae, Enterococcus faecalis, and Candida auris after 2 h of incubation. Viable titers of Clostridium difficile were reduced by 2.3, 3, and 4 logs after 2, 6, and 18 h, respectively. Infectious titers of HCoV-229E exposed to CMT for 2 h were reduced by 2.8 and 4 logs (99.85% and 99.99% reductions) as compared to Time-0 control and initial inoculum, respectively. The CMT retain their antibacterial efficacy even after 100 industrial washings. Use of cuprous oxide impregnated textiles in clinical settings may reduce not only hospital acquired infections caused by bacterial and fungal pathogens, but also, and equally important, those caused by coronavirus and other viruses. View Full-Text
Keywords: cuprous oxide; medical textiles; coronavirus; pathogens; hospital acquired infections cuprous oxide; medical textiles; coronavirus; pathogens; hospital acquired infections
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MDPI and ACS Style

Borkow, G.; Salvatori, R.; Kanmukhla, V.K. Drastic Reduction of Bacterial, Fungal and Viral Pathogen Titers by Cuprous Oxide Impregnated Medical Textiles. J. Funct. Biomater. 2021, 12, 9. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010009

AMA Style

Borkow G, Salvatori R, Kanmukhla VK. Drastic Reduction of Bacterial, Fungal and Viral Pathogen Titers by Cuprous Oxide Impregnated Medical Textiles. Journal of Functional Biomaterials. 2021; 12(1):9. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010009

Chicago/Turabian Style

Borkow, Gadi, Rachel Salvatori, and Vikram K. Kanmukhla 2021. "Drastic Reduction of Bacterial, Fungal and Viral Pathogen Titers by Cuprous Oxide Impregnated Medical Textiles" Journal of Functional Biomaterials 12, no. 1: 9. https://0-doi-org.brum.beds.ac.uk/10.3390/jfb12010009

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