Antibiotics, Volume 10, Issue 1 (January 2021) – 95 articles
Cover Story (view full-size image): There is growing interest in the use of non-antibiotic treatments for common bacterial infections. One such option is the use of cranberry extract for urinary tract infections (UTIs). Cranberry extract contains proanthocyanidins with A-type linkages; these polyphenols, or their metabolites, are believed to be the active ingredient inhibiting the binding of Escherichia coli to the uroepithelium. Multiple studies have assessed the use of cranberry extract in the prevention of UTIs, with mixed results. Fewer studies have assessed the potential for cranberry extract to treat an acute UTI, despite many women using cranberry products for this indication. Through systematic review, the authors synthesize the evidence for the use of cranberry products in the management of acute, uncomplicated UTIs. View this paper.
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