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Article

A Molecule of the Viridomycin Family Originating from a Streptomyces griseus-Related Strain Has the Ability to Solubilize Rock Phosphate and to Inhibit Microbial Growth

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Laboratory of Biotechnology and Valorization of Plant Genetic Resources, Faculty of Sciences and Techniques, University of Sultan Moulay Slimane, P.O. Box 523, Beni-Mellal 23000, Morocco
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INPT, Laboratoire de Génie Chimique, UMR 5503 (CNRS/INPT/UPS), École Nationale Supérieure d’Agronomie de Toulouse, 1, Avenue de l’Agrobiopôle, B.P. 107, F-31 326 Castanet-Tolosan CEDEX, France
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Laboratoire of Microbial Biotechnologies, Agrosciences and Environment, Université Cadi Ayyad (UCA), Boulevard Prince My Abdellah B.P. 2390, Marrakech 40000, Morocco
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AgroBioSciences Program, Mohammed VI Polytechnic University (UM6P), Benguerir 43150, Morocco
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CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, 91198 Gif-sur-Yvette, France
*
Author to whom correspondence should be addressed.
Received: 29 December 2020 / Revised: 10 January 2021 / Accepted: 12 January 2021 / Published: 14 January 2021
Some soil-borne microorganisms are known to have the ability to solubilize insoluble rock phosphate and this process often involves the excretion of organic acids. In this issue, we describe the characterization of a novel solubilizing mechanism used by a Streptomyces strain related to Streptomyces griseus isolated from Moroccan phosphate mines. This process involves the excretion of a compound belonging to the viridomycin family that was shown to play a major role in the rock phosphate bio weathering process. We propose that the chelation of the positively charged counter ions of phosphate constitutive of rock phosphate by this molecule leads to the destabilization of the structure of rock phosphate. This would result in the solubilization of the negatively charged phosphates, making them available for plant nutrition. Furthermore, this compound was shown to inhibit growth of fungi and Gram positive bacteria, and this antibiotic activity might be due to its strong ability to chelate iron, a metallic ion indispensable for microbial growth. Considering its interesting properties, this metabolite or strains producing it could contribute to the development of sustainable agriculture acting as a novel type of slow release bio-phosphate fertilizer that has also the interesting ability to limit the growth of some common plant pathogens. View Full-Text
Keywords: Streptomyces griseus; viridomycin; antimicrobial activity; rock phosphate solubilization Streptomyces griseus; viridomycin; antimicrobial activity; rock phosphate solubilization
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MDPI and ACS Style

Hamdali, H.; Lebrihi, A.; Monje, M.C.; Benharref, A.; Hafidi, M.; Ouhdouch, Y.; Virolle, M.J. A Molecule of the Viridomycin Family Originating from a Streptomyces griseus-Related Strain Has the Ability to Solubilize Rock Phosphate and to Inhibit Microbial Growth. Antibiotics 2021, 10, 72. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10010072

AMA Style

Hamdali H, Lebrihi A, Monje MC, Benharref A, Hafidi M, Ouhdouch Y, Virolle MJ. A Molecule of the Viridomycin Family Originating from a Streptomyces griseus-Related Strain Has the Ability to Solubilize Rock Phosphate and to Inhibit Microbial Growth. Antibiotics. 2021; 10(1):72. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10010072

Chicago/Turabian Style

Hamdali, Hanane, Ahmed Lebrihi, Marie C. Monje, Ahmed Benharref, Mohamed Hafidi, Yedir Ouhdouch, and Marie J. Virolle 2021. "A Molecule of the Viridomycin Family Originating from a Streptomyces griseus-Related Strain Has the Ability to Solubilize Rock Phosphate and to Inhibit Microbial Growth" Antibiotics 10, no. 1: 72. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10010072

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