Next Article in Journal
Electrolyte and Acid-Base Disorders Triggered by Aminoglycoside or Colistin Therapy: A Systematic Review
Next Article in Special Issue
Genomic Background and Phylogeny of cfiA-Positive Bacteroides fragilis Strains Resistant to Meropenem-EDTA
Previous Article in Journal
Prevalence of Vancomycin-Resistant Enterococcus (VRE) in Companion Animals: The First Meta-Analysis and Systematic Review
Previous Article in Special Issue
Clinical Presentation and Incidence of Anaerobic Bacteria in Surgically Treated Biliary Tract Infections and Cholecystitis
Article

The Prevalence and Clinical Significance of Anaerobic Bacteria in Major Liver Resection

Department of General, Visceral and Transplantation Surgery, University Hospital of Tuebingen, 72076 Tuebingen, Germany
*
Author to whom correspondence should be addressed.
Academic Editor: Fernando Cobo
Received: 6 January 2021 / Revised: 27 January 2021 / Accepted: 28 January 2021 / Published: 31 January 2021
(1) Background: Anaerobic infections in hepatobiliary surgery have rarely been addressed. Whereas infectious complications during the perioperative phase of liver resections are common, there are very limited data on the prevalence and clinical role of anaerobes in this context. Given the risk of contaminated bile in liver resections, the goal of our study was to investigate the prevalence and outcome of anaerobic infections in major hepatectomies. (2) Methods: We retrospectively analyzed the charts of 245 consecutive major hepatectomies that were performed at the department of General, Visceral, and Transplantation Surgery of the University Hospital of Tuebingen between July 2017 and August 2020. All microbiological cultures were screened for the prevalence of anaerobic bacteria and the patients’ clinical characteristics and outcomes were evaluated. (3) Results: Of the 245 patients, 13 patients suffered from anaerobic infections. Seven had positive cultures from the biliary tract during the primary procedure, while six had positive culture results from samples obtained during the management of complications. Risk factors for anaerobic infections were preoperative biliary stenting (p = 0.002) and bile leaks (p = 0.009). All of these infections had to be treated by intervention and adjunct antibiotic treatment with broad spectrum antibiotics. (4) Conclusions: Anaerobic infections are rare in liver resections. Certain risk factors trigger the antibiotic coverage of anaerobes. View Full-Text
Keywords: anaerobic infection; liver resection; cholangitis; biliary tract infection anaerobic infection; liver resection; cholangitis; biliary tract infection
Show Figures

Graphical abstract

MDPI and ACS Style

Strohäker, J.; Bareiß, S.; Nadalin, S.; Königsrainer, A.; Ladurner, R.; Meier, A. The Prevalence and Clinical Significance of Anaerobic Bacteria in Major Liver Resection. Antibiotics 2021, 10, 139. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10020139

AMA Style

Strohäker J, Bareiß S, Nadalin S, Königsrainer A, Ladurner R, Meier A. The Prevalence and Clinical Significance of Anaerobic Bacteria in Major Liver Resection. Antibiotics. 2021; 10(2):139. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10020139

Chicago/Turabian Style

Strohäker, Jens, Sophia Bareiß, Silvio Nadalin, Alfred Königsrainer, Ruth Ladurner, and Anke Meier. 2021. "The Prevalence and Clinical Significance of Anaerobic Bacteria in Major Liver Resection" Antibiotics 10, no. 2: 139. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10020139

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop