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Review

Blue Light Disinfection in Hospital Infection Control: Advantages, Drawbacks, and Pitfalls

by 1,* and 1,2
1
Division of Microbiology, Department of Pathology, Porto Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
2
CINTESIS—Center for Health Technology and Services Research, 4200-450 Porto, Portugal
*
Author to whom correspondence should be addressed.
Received: 19 March 2019 / Revised: 27 April 2019 / Accepted: 2 May 2019 / Published: 7 May 2019
(This article belongs to the Special Issue Photodynamic Therapy in the Inactivation of Microorganisms)
Hospital acquired infections (HAIs) are a serious problem that potentially affects millions of patients whenever in contact with hospital settings. Worsening the panorama is the emergence of antimicrobial resistance by most microorganisms implicated in HAIs. Therefore, the improvement of the actual surveillance methods and the discovery of alternative approaches with novel modes of action is vital to overcome the threats created by the emergence of such resistances. Light therapy modalities represent a viable and effective alternative to the conventional antimicrobial treatment and can be preponderant in the control of HAIs, even against multidrug resistant organisms (MDROs). This review will initially focus on the actual state of HAIs and MDROs and which methods are currently available to fight them, which is followed by the exploration of antimicrobial photodynamic therapy (aPDT) and antimicrobial blue light therapy (aBLT) as alternative approaches to control microorganisms involved in HAIs. The advantages and drawbacks of BLT relatively to aPDT and conventional antimicrobial drugs as well as its potential applications to destroy microorganisms in the healthcare setting will also be discussed. View Full-Text
Keywords: hospital acquired infection; multi-drug resistant organisms; infection control; photodynamic therapy; photosensitizer; porphyrins; blue light therapy hospital acquired infection; multi-drug resistant organisms; infection control; photodynamic therapy; photosensitizer; porphyrins; blue light therapy
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MDPI and ACS Style

Cabral, J.; AG, R. Blue Light Disinfection in Hospital Infection Control: Advantages, Drawbacks, and Pitfalls. Antibiotics 2019, 8, 58. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics8020058

AMA Style

Cabral J, AG R. Blue Light Disinfection in Hospital Infection Control: Advantages, Drawbacks, and Pitfalls. Antibiotics. 2019; 8(2):58. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics8020058

Chicago/Turabian Style

Cabral, João, and Rodrigues AG. 2019. "Blue Light Disinfection in Hospital Infection Control: Advantages, Drawbacks, and Pitfalls" Antibiotics 8, no. 2: 58. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics8020058

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