Antibiotics Differentially Modulate Lipoteichoic Acid-Mediated Host Immune Response
Abstract
:1. Introduction
2. Results
2.1. Purified LTA from S. aureus Differentially Affected Expression of Cytokine and Cell Surface Markers in a Dose-Dependent Manner in Human PBMCs
2.2. Antibiotics Exert Drug- and Dose-Dependent LTA-Mediated Effects on Cytokine and Cell Surface Marker Expression in Human PBMCs
3. Discussion
4. Materials and Methods
4.1. Isolation of Peripheral Blood Mononuclear Cells (PBMCs)
4.2. Cell Culture and Stimulation
4.3. Cytokine Quantification by ELISA
4.4. Immune Cell Surface Marker Expression by Flow Cytometry
4.5. Statistical Analysis
Author Contributions
Funding
Conflicts of Interest
References
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Algorri, M.; Wong-Beringer, A. Antibiotics Differentially Modulate Lipoteichoic Acid-Mediated Host Immune Response. Antibiotics 2020, 9, 573. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics9090573
Algorri M, Wong-Beringer A. Antibiotics Differentially Modulate Lipoteichoic Acid-Mediated Host Immune Response. Antibiotics. 2020; 9(9):573. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics9090573
Chicago/Turabian StyleAlgorri, Marquerita, and Annie Wong-Beringer. 2020. "Antibiotics Differentially Modulate Lipoteichoic Acid-Mediated Host Immune Response" Antibiotics 9, no. 9: 573. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics9090573