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Review

Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects

1
Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University, Emek, Ankara 06490, Turkey
2
Department of Nutrition and Dietetics, Faculty of Health Sciences, Çukurova University, Sarıçam, Adana 01330, Turkey
3
Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy
*
Authors to whom correspondence should be addressed.
Academic Editors: Marwan El Ghoch, Agnes Ayton and Maurizio Battino
Received: 12 July 2021 / Revised: 11 September 2021 / Accepted: 23 September 2021 / Published: 23 September 2021
(This article belongs to the Special Issue The Relationship between Nutrition and Diseases)
Helicobacter pylori (H. pylori) is a 0.5–1 µm wide, 2–4 µm long, short helical, S-shaped Gram-negative microorganism. It is mostly found in the pyloric region of the stomach and causes chronic gastric infection. It is estimated that these bacteria infect more than half of the world’s population. The mode of transmission and infection of H. pylori is still not known exactly, but the faecal–oral and oral–oral routes via water or food consumption are thought to be a very common cause. In the last three decades, research interest has increased regarding the pathogenicity, microbial activity, genetic predisposition, and clinical treatments to understand the severity of gastric atrophy and gastric cancer caused by H. pylori. Studies have suggested a relationship between H. pylori infection and malabsorption of essential micronutrients, and noted that H. pylori infection may affect the prevalence of malnutrition in some risk groups. On the other hand, dietary factors may play a considerably important role in H. pylori infection, and it has been reported that an adequate and balanced diet, especially high fruit and vegetable consumption and low processed salty food consumption, has a protective effect against the outcomes of H. pylori infection. The present review provides an overview of all aspects of H. pylori infection, such as clinical features, treatment, and nutrition. View Full-Text
Keywords: H. pylori; nutrition; infection; diet; clinical treatment H. pylori; nutrition; infection; diet; clinical treatment
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MDPI and ACS Style

Öztekin, M.; Yılmaz, B.; Ağagündüz, D.; Capasso, R. Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects. Diseases 2021, 9, 66. https://0-doi-org.brum.beds.ac.uk/10.3390/diseases9040066

AMA Style

Öztekin M, Yılmaz B, Ağagündüz D, Capasso R. Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects. Diseases. 2021; 9(4):66. https://0-doi-org.brum.beds.ac.uk/10.3390/diseases9040066

Chicago/Turabian Style

Öztekin, Merve, Birsen Yılmaz, Duygu Ağagündüz, and Raffaele Capasso. 2021. "Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects" Diseases 9, no. 4: 66. https://0-doi-org.brum.beds.ac.uk/10.3390/diseases9040066

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