Metabolites, Volume 11, Issue 2 (February 2021) – 68 articles
Cover Story (view full-size image): The in utero environment during pregnancy has important implications for the developing health of the child. In mother–child pairs from the Vitamin D Antenatal Asthma Reduction Trial, we assessed the prospective relationship between maternal metabolites from 10–18-week and 32–38-week gestation, respectively, and the risk of child asthma or recurrent wheeze by age three. Coffee-related metabolites in the maternal metabolome appeared to be of particular interest (inverse associations observed). Additional observations also highlighted steroid and sphingolipid metabolites. Our results suggest that alterations in prenatal metabolites may play a role in the development of offspring asthma. View this paper
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