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Article

Making a Decision between Acute Appendicitis and Acute Gastroenteritis

1
Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan
2
Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan
3
Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
4
Department of Pediatrics, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
*
Author to whom correspondence should be addressed.
Received: 9 September 2020 / Revised: 3 October 2020 / Accepted: 6 October 2020 / Published: 11 October 2020
Acute appendicitis is one of the most common pediatric abdominal emergencies. Early diagnosis is vital for a positive outcome. However, it may initially present with diarrhea and vomiting, mimicking acute gastroenteritis, thus delaying prompt surgery. Differentiating appendicitis from gastroenteritis in a timely manner poses a challenge. Therefore, we aim to investigate the predictors that help distinguish acute appendicitis from acute gastroenteritis. We conducted a retrospective case-control study, evaluating children admitted due to abdominal pain with diarrhea. Subjects were divided into two groups according to the final diagnoses: acute appendicitis and acute gastroenteritis. We adopted multiple logistic regression analysis and the area under the receiver operating characteristic curve to identify independent predictors of acute appendicitis and select the best model. A total of 32 patients diagnosed with appendicitis and 82 patients with gastroenteritis were enrolled. Five independent predictors of acute appendicitis included vomiting, right lower quadrant (RLQ) pain, stool occult blood (OB), white blood cell (WBC) count, and C-reactive protein (CRP). The revised combined model exhibited a higher degree of discrimination and outperformed the pediatric appendicitis score (PAS) model. In conclusion, our study was proved to be helpful for assessing cases with abdominal pain and diarrhea in order to more accurately distinguish appendicitis from gastroenteritis in children in a timely manner. View Full-Text
Keywords: acute appendicitis; gastroenteritis; abdominal pain; diarrhea acute appendicitis; gastroenteritis; abdominal pain; diarrhea
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MDPI and ACS Style

Lu, Y.-T.; Chen, P.-C.; Huang, Y.-H.; Huang, F.-C. Making a Decision between Acute Appendicitis and Acute Gastroenteritis. Children 2020, 7, 176. https://0-doi-org.brum.beds.ac.uk/10.3390/children7100176

AMA Style

Lu Y-T, Chen P-C, Huang Y-H, Huang F-C. Making a Decision between Acute Appendicitis and Acute Gastroenteritis. Children. 2020; 7(10):176. https://0-doi-org.brum.beds.ac.uk/10.3390/children7100176

Chicago/Turabian Style

Lu, Yi-Ting, Po-Cheng Chen, Ying-Hsien Huang, and Fu-Chen Huang. 2020. "Making a Decision between Acute Appendicitis and Acute Gastroenteritis" Children 7, no. 10: 176. https://0-doi-org.brum.beds.ac.uk/10.3390/children7100176

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