Next Article in Journal
A Cost Analysis of an Outreach School-Based Dental Program: Teeth on Wheels
Next Article in Special Issue
Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model
Previous Article in Journal
The Feasibility of Studying Metabolites in PICU Multi-Organ Dysfunction Syndrome Patients over an 8-Day Course Using an Untargeted Approach

Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia

Section of Pediatric Pulmonology, Allergy and Sleep Medicine, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN 46202, USA
Author to whom correspondence should be addressed.
Academic Editors: Roberto W. Dal Negro and Rita Marie Ryan
Received: 29 December 2020 / Revised: 8 February 2021 / Accepted: 10 February 2021 / Published: 18 February 2021
(This article belongs to the Special Issue Neonatal Respiratory Distress)
Primary ciliary dyskinesia (PCD) is inherited in a predominantly autosomal recessive manner with over 45 currently identified causative genes. It is a clinically heterogeneous disorder that results in a chronic wet cough and drainage from the paranasal sinuses, chronic otitis media with hearing impairment as well as male infertility. Approximately 50% of patients have situs inversus totalis. Prior to the development of chronic oto-sino-pulmonary symptoms, neonatal respiratory distress occurs in more than 80% of patients as a result of impaired mucociliary clearance and mucus impaction causing atelectasis and lobar collapse. Diagnosis is often delayed due to overlapping symptoms with other causes of neonatal respiratory distress. A work up for PCD should be initiated in the newborn with compatible clinical features, especially those with respiratory distress, consistent radiographic findings or persistent oxygen requirement and/or organ laterality defects View Full-Text
Keywords: primary ciliary dyskinesia; neonatal respiratory distress primary ciliary dyskinesia; neonatal respiratory distress
Show Figures

Figure 1

MDPI and ACS Style

Machogu, E.; Gaston, B. Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia. Children 2021, 8, 153.

AMA Style

Machogu E, Gaston B. Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia. Children. 2021; 8(2):153.

Chicago/Turabian Style

Machogu, Evans, and Benjamin Gaston. 2021. "Respiratory Distress in the Newborn with Primary Ciliary Dyskinesia" Children 8, no. 2: 153.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop