Atypical Fibroxanthoma-Like Amelanotic Melanoma: A Diagnostic Challenge
Section of Pathology, Department of Emergency and Organ Transplantation, University of Bari, 70121 Bari, Italy
Section of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 70121 Bari, Italy
Author to whom correspondence should be addressed.
Dermatopathology 2021, 8(1), 25-28; https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8010004
Received: 14 December 2020 / Revised: 7 January 2021 / Accepted: 8 January 2021 / Published: 12 January 2021
(This article belongs to the Section Clinico-Pathological Correlation in Dermatopathology)
Atypical fibroxanthoma-like amelanotic melanoma is a very rare variant of melanoma that can, if not correctly recognized and framed, lead to diagnostic errors that can potentially cause problems of extreme relevance to patients. Correct knowledge of this entity and the execution of adequate immunohistochemical investigations are the basic conditions for the correct management of this lesion. We report on a case of atypical fibroxanthoma-like amelanotic melanoma, which clinically simulated a fibrohistiocytic lesion, and which created differential diagnostic problems, and finally, we conduct a short review of the literature.