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How to Deal with Skin Biopsy in an Infant with Blisters?

Reference Center for Genodermatoses (MAGEC Center), Department of Pathology, Necker-Enfants Malades Hospital, Paris Centre University, 75015 Paris, France
Academic Editor: Gürkan Kaya
Received: 3 May 2021 / Revised: 31 May 2021 / Accepted: 1 June 2021 / Published: 4 June 2021
(This article belongs to the Special Issue New Insights in Pediatric Dermatopathology)
The onset of blisters in a neonate or an infant is often a source of great concern for both parents and physicians. A blistering rash can reveal a wide range of diseases with various backgrounds (infectious, genetic, autoimmune, drug-related, traumatic, etc.), so the challenge for the dermatologist and the pediatrician is to quickly determine the etiology, between benign causes and life-threatening disorders, for a better management of the patient. Clinical presentation can provide orientation for the diagnosis, but skin biopsy is often necessary in determining the cause of blister formations. In this article, we will provide information on the skin biopsy technique and discuss the clinical orientation in the case of a neonate or infant with a blistering eruption, with a focus on the histology for each etiology. View Full-Text
Keywords: blistering eruption; infant; skin biopsy; genodermatosis; SSSS; hereditary epidermolysis bullosa; keratinopathic ichthyosis; incontinentia pigmenti; mastocytosis; auto-immune blistering diseases blistering eruption; infant; skin biopsy; genodermatosis; SSSS; hereditary epidermolysis bullosa; keratinopathic ichthyosis; incontinentia pigmenti; mastocytosis; auto-immune blistering diseases
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MDPI and ACS Style

Leclerc-Mercier, S. How to Deal with Skin Biopsy in an Infant with Blisters? Dermatopathology 2021, 8, 159-175. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020022

AMA Style

Leclerc-Mercier S. How to Deal with Skin Biopsy in an Infant with Blisters? Dermatopathology. 2021; 8(2):159-175. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020022

Chicago/Turabian Style

Leclerc-Mercier, Stéphanie. 2021. "How to Deal with Skin Biopsy in an Infant with Blisters?" Dermatopathology 8, no. 2: 159-175. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020022

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