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Case Report

Insidious-Onset Indurated Plaques on the Shins

1
Imperial College School of Medicine, Imperial College London, South Kensington, London SW7 2BU, UK
2
Departments of Dermatology, Cleveland Clinic, Cleveland, OH 44195, USA
3
Departments of Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Gürkan Kaya
Received: 13 May 2021 / Revised: 4 June 2021 / Accepted: 5 June 2021 / Published: 6 June 2021
A 64-year old male presented with a several-year history of an insidious-onset tender, itchy and xerotic rash on his lower legs. Past medical history was significant for Graves’ disease and Graves’ ophthalmopathy. The examination revealed peau d’orange-appearing plaques on his shins clinically consistent with pretibial myxedema. A punch biopsy showed separation of collagen bundles with extensive dermal mucin deposition, confirming the diagnosis of pretibial myxedema. After initially failing treatment with a topical clobetasol 0.05% ointment, the patient switched to regular pentoxifylline and triamcinolone 0.1% ointment under occlusion. He remains under follow-up. View Full-Text
Keywords: Graves’ disease; pretibial myxedema; mucin Graves’ disease; pretibial myxedema; mucin
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MDPI and ACS Style

Agrawal, R.; Knabel, D.; Fernandez, A.P. Insidious-Onset Indurated Plaques on the Shins. Dermatopathology 2021, 8, 185-189. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020024

AMA Style

Agrawal R, Knabel D, Fernandez AP. Insidious-Onset Indurated Plaques on the Shins. Dermatopathology. 2021; 8(2):185-189. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020024

Chicago/Turabian Style

Agrawal, Rishi, Daniel Knabel, and Anthony P. Fernandez 2021. "Insidious-Onset Indurated Plaques on the Shins" Dermatopathology 8, no. 2: 185-189. https://0-doi-org.brum.beds.ac.uk/10.3390/dermatopathology8020024

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