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Article

Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion

Department of Prosthodontics & Oral Rehabilitation, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto, Tokushima 770-8504, Japan
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Received: 15 July 2020 / Revised: 25 August 2020 / Accepted: 31 August 2020 / Published: 2 September 2020
(This article belongs to the Special Issue Salivary Medicine and Regeneration of Salivary Glands)
In this study, we evaluated the reliability and reproducibility of widely implemented salivary flow rate and oral dryness tests. In experiment 1, twenty young and healthy Japanese participants volunteered to participate. For each participant, the oral moisture (OM) level, unstimulated whole saliva volume (U-WSV), and stimulated whole saliva volume (S-WSV) were measured at the same time on two separate days. In experiment 2, twenty-seven patients who were over 65 years of age volunteered to participate. The OM level and U-WSV were measured at the same time on two separate days. In Experiment 1, the intra-class correlation coefficients (ICCs) corresponding to the S-WSV, U-WSV, and OM level were 0.23, 0.28, and 0.16, respectively, for the young participants. In Experiment 2, the ICCs corresponding to the U-WSV/spitting and OM level were 0.83 and 0.12, respectively, for the older participants. The results of Bland–Altman analysis confirmed the absence of systematic error, with the exception of the OM level results in Experiment 2, which indicated systematic bias. In conclusion, we believe that there is currently no consistent and reliable screening test for assessing salivary flow rate and oral dryness, although the spitting test was determined to be highly reliable. View Full-Text
Keywords: unstimulated whole saliva volume; stimulated whole saliva volume; oral moisture level; intra-class correlation coefficients; Bland–Altman analysis unstimulated whole saliva volume; stimulated whole saliva volume; oral moisture level; intra-class correlation coefficients; Bland–Altman analysis
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MDPI and ACS Style

Goto, T.; Kishimoto, T.; Iwawaki, Y.; Fujimoto, K.; Ishida, Y.; Watanabe, M.; Nagao, K.; Ichikawa, T. Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion. Dent. J. 2020, 8, 102. https://0-doi-org.brum.beds.ac.uk/10.3390/dj8030102

AMA Style

Goto T, Kishimoto T, Iwawaki Y, Fujimoto K, Ishida Y, Watanabe M, Nagao K, Ichikawa T. Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion. Dentistry Journal. 2020; 8(3):102. https://0-doi-org.brum.beds.ac.uk/10.3390/dj8030102

Chicago/Turabian Style

Goto, Takaharu, Takahiro Kishimoto, Yuki Iwawaki, Keiko Fujimoto, Yuichi Ishida, Megumi Watanabe, Kan Nagao, and Tetsuo Ichikawa. 2020. "Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion" Dentistry Journal 8, no. 3: 102. https://0-doi-org.brum.beds.ac.uk/10.3390/dj8030102

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